基本説明
Provides a comprehensive overview of timely topics covering the relationships between the immune system and the pathogenesis of neurodegenerative disorders.
Full Description
Neuroimmune pharmacology seeks to harness the immune system to provide pharmacological intervention to combat neurodegenerative diseases. This book provides a comprehensive overview of topics that embrace the link between the immune system and the pathogenesis of neurodegenerative disorders. Results from recent studies strongly suggest that a major part of the process in diseases including Alzheimer's and Parkinson's as well as Prion diseases, comes from changes in the innate and adaptive arms of the brain and peripheral immune systems. Thus, the book provides an in-depth study of numerous fields including immunology, pharmacology, neuroscience and neurovirology. It is accompanied by a CD-ROM that includes access to lectures, slide presentations, and question and answers on neuroimmune pharmacology.
Contents
Immunology of the Nervous System.- Introducing Neuroimmune Pharmacology.- Innate and Adaptive Immunity in Health and Disease.- Anatomical Networks: Structure and Function of the Nervous System.- The Blood Brain Barrier.- Anterior Chamber and Retina.- Hippocampus and Spatial Memory.- Glial and Neuronal Cellular Compostion, Biology, and Physiology.- Astrocytes, Oligodendrocytes, and Schwann Cells.- Macrophages, Microglia, and Dendritic C.- Neuronal and Glial Signaling.- The Vertebrate Retina.- Lymphocytes and the Nervous System.- Stem Cells.- Neurobiology and Neural Systems.- Cytokines and Chemokines.- CNS Cell Signaling.- Nervous System Diseases and Immunity: Clinical Descriptions.- Neurodegeneration.- Multiple Sclerosis and Other Demyelinating Diseases.- Guillain-Barre Syndrome, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, and Axonal Degeneration and Regeneration.- Guillain-Barre Syndrome.- Autoimmune Disease.- NeuroAIDS.- HTLV-I/II.- Viral Encephalitis.- Alzheimer's Disease.- Parkinson's Disease.- Amyotrophic Lateral Sclerosis.- Huntington's Disease.- Prion Diseases.- Glaucoma.- Stroke and Cerebrovascular Disease.- Neurogenesis and Brain Repair.- Familial Neurodegenerative Diseases and Single Nucleotide Polymorphisms.- The Neuroimmune System in Psychiatric Disorders.- Major Depression, Bipolar Syndromes, and Schizophrenia.- Molecular Pathogenesis for Schizophrenia and Major Depression.- Drugs of Abuse and the Immune System.- Therapeutics.- Neuropharmacology.- Neurodegenerative Diseases.- Multiple Sclerosis.- HIV-Associated Dementia.- Immunotherapy.- Alzheimer's Disease.- Parkinson's Disease and Amyotrophic Lateral Sclerosis.- Protective and Regenerative Autoimmunity in CNS Injury.- Adjuvants.- Polymer Nanomaterials.- Gene Therapy and Vaccination.- Proteomics and Genomics.- Neuroimaging.
