Ⅱ：ゲノミクス・プロテオミクスのためのマイクロ・ナノテクノロジー BioMEMS and Biomedical Nanotechnology Vol.2 : Micro-and-Nano-Technologies for Genomics and Proteomics （2006. XX, 540 p. w. 104 figs. (10 col.)）

Ⅱ：ゲノミクス・プロテオミクスのためのマイクロ・ナノテクノロジー<br>BioMEMS and Biomedical Nanotechnology Vol.2 : Micro-and-Nano-Technologies for Genomics and Proteomics （2006. XX, 540 p. w. 104 figs. (10 col.)）

個数：

Ⅱ：ゲノミクス・プロテオミクスのためのマイクロ・ナノテクノロジー
BioMEMS and Biomedical Nanotechnology Vol.2 : Micro-and-Nano-Technologies for Genomics and Proteomics （2006. XX, 540 p. w. 104 figs. (10 col.)）

Ed. by Mihrimah Ozkan, Michael Heller and Mauro Ferrari

ウェブストア価格 ¥46,151（本体¥41,956）
springer（2006発売）
外貨定価 US$ 219.99
ポイント 419pt

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製本 Hardcover:ハードカバー版／ページ数 420 p.
言語 ENG
商品コード 9780387255644

Full Description

Less than twenty years ago photolithography and medicine were total strangers to one another.Theyhadnotyetmet,andnotevenlookingeachotherupintheclassi?eds.And then,nucleicacidchips,micro?uidicsandmicroarraysenteredthescene,andrapidlythese strangersbecameindispensablepartnersinbiomedicine. Asrecentlyastenyearsagothenotionofapplyingnanotechnologytothe?ghtagainstd- easewasdominantlytheprovinceofthe?ctionwriters.Thoughtsofnanoparticle-vehicled deliveryoftherapeuticalstodiseasedsiteswereanexerciseinscienti?csolitude,andgrounds for questioning one's ability to think "like an established scientist". And today we have nanoparticulatepaclitaxelastheprimeoptionagainstmetastaticbreastcancer,proteomic pro?lingdiagnostictoolsbasedontargetsurfacenanotexturing,nanoparticlecontrastagents forallradiologicalmodalities,nanotechnologiesembeddedinhigh-distributionlaboratory equipment, and no less than 152 novel nanomedical entities in the regulatory pipeline in theUSalone. Thisisatransformingimpact,byanymeasure,withclearevidenceoffurtheracceleration, supported by very vigorous investments by the public and private sectors throughout the world.
Even joining the dots in a most conservative, linear fashion, it is easy to envision scenariosofpersonalizedmedicinesuchasthefollowing: patient-speci?cpreventionsupplantinggross,facelessinterventionstrategies; early detection protocols identifying signs of developing disease at the time when thediseaseismosteasilysubdued; personally tailored intervention strategies that are so routinely and inexpensively realized,thataccesstothemcanbesecuredbyeveryone; technologiesallowingforlonglivesinthecompanyofdisease,asgoodneighbors, withoutimpairmentofthequalityoflifeitself. Thesevisionswillbecomereality.Thecontributionsfromtheworldsofsmall-scalete- nologies are required to realize them. Invaluable progress towards them was recorded by the very scientists that have joined forces to accomplish the effort presented in this 4-volume collection. It has been a great privilege for me to be at their service, and at the service of the readership, in aiding with its assembly. May I take this oppor- nity to express my gratitude to all of the contributing Chapter Authors, for their - spired and thorough work. For many of them, writing about the history of their s- cialty?eldsofBioMEMSandBiomedicalNanotechnologyhasreallybeenreportingabout their personal, individual adventures through scienti?
c discovery and innovation-a sort xxii FOREWORD of family album, with equations, diagrams, bibliographies and charts replacing Holiday pictures...

Application of Microarray Technologies.- Electronic Microarray Technology and Applications in Genomics and Proteomics.- Gene Expression Profiling Utilizing Microarray Technology and RT-PCR.- Microarray and Fluidic Chip for Extracellular Sensing.- Cell Physiometry Tools based on Dielectrophoresis.- Hitting the Spot: The Promise of Protein Microarrays.- Use of Electric Field Array Devices for Assisted Assembly of DNA Nanocomponents and Other Nanofabrication Applications.- Peptide Arrays in Proteomics and Drug Discovery.- From One-Bead One-Compound Combinatorial Libraries to Chemical Microarrays.- Advanced Microfluidic Devices and Human Genome Project.- Plastic Microfluidic Devices for DNA and Protein Analyses.- Centrifuge Based Fluidic Platforms.- Sequencing the Human Genome: A Historical Perspective on Challenges for Systems Integration.- Nanoprobes for Imaging, Sensing and Therapy.- Hairpin Nanoprobes for Gene Detection.- Fluorescent Lanthanide Labels with Time-Resolved Fluorometry in DNA Analysis.- Role of SNPs and Haplotypes in Human Disease and Drug Development.- Control of Biomolecular Activity by Nanoparticle Antennas.- Sequence Matters: The Influence of Basepair Sequence on DNA-protein Interactions.- Engineered Ribozymes: Efficient Tools for Molecular Gene Therapy and Gene Discovery.