Metal Ions in Biochemistry （2ND）

個数：

Metal Ions in Biochemistry （2ND）

  • 提携先の海外書籍取次会社に在庫がございます。通常3週間で発送いたします。
    【重要ご説明事項】
    1. 納期遅延や、ご入手不能となる場合が若干ございます。
    2. 複数冊ご注文の場合は、ご注文数量が揃ってからまとめて発送いたします。
    3. 美品のご指定は承りかねます。

    ●3Dセキュア導入とクレジットカードによるお支払いについて
  • 【入荷遅延について】
    世界情勢の影響により、海外からお取り寄せとなる洋書・洋古書の入荷が、表示している標準的な納期よりも遅延する場合がございます。
    おそれいりますが、あらかじめご了承くださいますようお願い申し上げます。
  • ◆画像の表紙や帯等は実物とは異なる場合があります。
  • ◆ウェブストアでの洋書販売価格は、弊社店舗等での販売価格とは異なります。
    また、洋書販売価格は、ご注文確定時点での日本円価格となります。
    ご注文確定後に、同じ洋書の販売価格が変動しても、それは反映されません。
  • 製本 Paperback:紙装版/ペーパーバック版／ページ数 274 p.
  • 言語 ENG
  • 商品コード 9780367622244
  • DDC分類 572.51

Full Description

The second edition of Metal Ions in Biochemistry deals with the multidisciplinary subject of bio-inorganic chemistry, encompassing the disciplines of inorganic chemistry, biochemistry and medicine.

The book deals with the role of metal ions in biochemistry, emphasising that biochemistry is mainly the chemistry of metal-biochemical complexes. Hence, the book starts with the structures of biochemicals and the identification of their metal binding sites. Thermodynamic and kinetic properties of the complexes are explained from the point of view of the nature of metal-ligand bonds. Various catalytic and structural roles of metal ions in biochemicals are discussed in detail.

Features




The role of Na+ and K+ in brain chemistry.



The role of zinc insulin in glucose metabolism and its enhancement by vanadium and chromium compounds.



Discussion of the role of zinc signals, zinc fingers and cascade effect in biochemistry.



Haemoglobin synthesis and the role of vitamin B12 in it.



The role of lanthanides in biochemical systems.



A detailed discussion of the role of non-metals in biochemistry, a topic missing in most of the books on bio-inorganic chemistry.

The study of bio-inorganic chemistry makes biochemists rethink the mechanistic pathways of biochemical reactions mediated by metal ions. There is a realisation of the role of metal complexes and inorganic ions as therapeutics such as iron in leukaemia, thalassemia and sickle cell anaemia, iodine in hypothyroidism and zinc, vanadium and chromium in glucose metabolism. The most recent realisation is of the use of zinc in the prevention and treatment of COVID-19.

Contents

1. Structure of Cells and Introduction to Bioinorganic Chemistry................................................. 1

2. Thermodynamic and Kinetic Properties of Metal Complexes....................................................17

3 Alkali and Alkaline Earth Metal Ions in Biochemical Systems................................................. 63

4. Zinc in Biochemical Systems.......................................................................................................... 83

5. Iron in Biochemical Systems........................................................................................................ 103

6. Copper in Biochemical Systems................................................................................................... 139

7. Cobalt in Vitamin B12 in Biochemical System............................................................................ 157

8. Molybdenum in Nitrogen Fixation in Plants...............................................................................167

9. Magnesium and Manganese in Photosynthesis in Plants...........................................................177

10. Less Common Trace Metal Ions in Biochemical Systems..........................................................187

11. Metal Ion Toxicity in Biochemical Systems................................................................................ 209

12. Metal Complexes in Therapeutics................................................................................................219

13. Role of Trace Nonmetals in Biochemical Systems......................................................................231