Multicomponent Reactions : Synthesis of Bioactive Heterocycles

Ameta, Ph.D. (EDT)/ Dandia, Anshu (EDT)

CRC Press（2020/08発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 394 p.
• 言語 ENG
• 商品コード 9780367573126
• DDC分類 547.59

Full Description

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.

Contents

MCR for carbon-carbon and carbon-heteroatom coupling reactions. MCR for cycloadditions, and other related reactions. MCR as promising tool for the synthesis of bioactive heterocycles: Pyrazole.MCR as promising tool for the synthesis of bioactive heterocycles: Imidazole. MCR as promising tool for the synthesis of bioactive heterocycles: Isoxazole. MCR as promising tool for the synthesis of bioactive heterocycles: Oxazole. MCR as promising tool for the synthesis of bioactive heterocycles: Thiazole. MCR as promising tool for the synthesis of bioactive heterocycles: Isothiazole. MCR as promising tool for the synthesis of bioactive heterocycles: Benzimidazole. MCR as promising tool for the synthesis of bioactive heterocycles: Sulfathiazole.