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Full Description
We have come to realize that optimal nutrient intake is determined by very specific genetic messages. This realization has led to an entirely new approach to understanding nutrition - the exploration of nutrient effects on gene expression.
Edited by leading experts in the field, Nutrient-Gene Interactions in Health and Disease provides an update of this important and rapidly growing field of research, presenting examples of both macronutrients and micronutrients as they affect gene expression. It addresses lipogenesis, fatty acid oxidation, fatty acid desaturation, and glucose transporters. It also discusses genes that associate with obesity or cancer, genes that are affected by vitamins A and D, and several other topics.
Genetic regulation of nutritional response is at the heart of our understanding of nutrition science. Nutrient-Gene Interactions in Health and Disease presents the latest information about how specific processes in intermediary metabolism are genetically regulated, giving you a new understanding of such diseases as obesity, diabetes, alcoholism, anemia, and other diseases with both a nutrient and a genetic component.
Contents
Dietary and Hormonal Regulation of the Mammalian Fatty Acid Synthase Gene. Nutrition and Adipocyte Gene Expression. Regulation of the Stearoyl-CoA Desaturase Genes by Dietary Fat. Fatty Acids, White Adipose Tissue Development and Adipocyte Differentiation. Acyl-CoA Synthetase 1. Nutritional Regulation of Fatty Acid Transport Protein Expression. Alcohol and Gene Expression in the Central Nervous System. Nutrient Control of Insulin-Stimulated Glucose Transport in 3T3-L1 Adipocytes. Prohormone Processing and Disorders of Energy Homeostasis. The Agouti Gene in Obesity. Dietary Fats and APC-Driven Intestinal Tumorigenesis. Body Weight Regulation, Uncoupling Proteins, and Energy Metabolism. Vitamin A and Gene Expression. Vitamin A and Mitochondrial Gene Expression. Vitamin D and Gene Expression. Vitamin E and Gene Expression. Differential Regulation and Function of Glutathione Peroxidases and other Selenoproteins. Ferritin.
