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Full Description
This cutting-edge reference clearly explains pharmaceutical transport phenomena, demonstrating applications ranging from drug or nutrient uptake into vesicle or cell suspensions, drug dissolution and absorption across biological membranes, whole body kinetics, and drug release from polymer reservoirs and matrices to heat and mass transport in freeze-drying and hygroscopicity.
Focuses on practical applications of drug delivery from a physical and mechanistic perspective, highlighting biological systems.
Written by more than 30 international authorities in the field, Transport Processes in Pharmaceutical Systems
discusses the crucial relationship between the transport process and thermodynamic factors
analyzes the dynamics of diffusion at liquid-liquid, liquid-solid, and liquid-cultured cell interfaces
covers prodrug design for improving membrane transport
addresses the effects of external stimuli in altering some natural and synthetic polymer matrices
examines properties of hydrogels, including synthesis, swelling degree, swelling kinetics, permeability, biocompatibility, and biodegradability
presents mass transfer of drugs and pharmacokinetics based on mass balance descriptions
and more!
Containing over 1000 references and more than 1100 equations, drawings, photographs, micrographs, and tables, Transport Processes in Pharmaceutical Systems is a must-read resource for research pharmacists, pharmaceutical scientists and chemists, chemical engineers, physical chemists, and upper-level undergraduate and graduate students in these disciplines.
Contents
Introduction to Transport Processes Principles of Mass Transfer Elizabeth M. Topp Analytical Solutions to Mass Transfer Lawrence X. Yu and Gordon L. Amidon Pharmacokinetics: Model Structure and Transport Systems James M. Gallo Experimental Methods to Evaluate Diffusion Coefficients and Investigate Transport Processes of Pharmaceutical Interest John W. Mauger Dissolution of Pharmaceuticals in Simple and Complex Systems Daniel P. McNamara, Michael L. Vieira, and John R. Crison Biological Transport Processes Biological Transport Phenomena in the Gastrointestinal Tract: Cellular Mechanisms David Fleisher Improving Oral Drug Transport via Prodrugs Mandana Asgharnejad Quantitative Approaches to Delineate Passive Transport Mechanisms in Cell Culture Monolayers Norman F. H. Ho, Thomas J. Raub, Phillip S. Burton, Craig L. Barsuhn, Anthony Adson, Kenneth L. Audus, and Ronald T. Borchardt Barriers to Drug Transport in Ocular Epithelia Uday B. Kompella and Vincent H. L. Lee Predicting Oral Drug Absorption in Humans Lawrence Yu, Larry Gatlin, and Gordon L. Amidon Transport Processes in Polymer Systems Controlled Release Osmotic Drug Delivery Systems for Oral Applications John R. Cardinal Transport in Polymer Systems Jim H. Kou Synthesis and Properties of Hydrogels Used for Drug Delivery Stevin H. Gehrke Stimuli-Modulated Delivery Systems Sung Wan Kim and You Han Bae Properties of Solids that Affect Transport Manesh J. Nerurkar, Sarma Duddu, David J. W. Grant, and J. Howard Rytting Heat and Mass Transport Heat and Mass Transfer in Low Pressure Gases: Applications to Freeze Drying Michael J. Pikal Heat and Mass Transport: Hygroscopicity James Wright
