Molecular and Cellular Mechanisms of Toxicity (Routledge Revivals) -- Paperback / softback

De Matteis, Francesco

Taylor & Francis Ltd（2020/12発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 224 p.
• 言語 ENG
• 商品コード 9780367229146
• DDC分類 615

Full Description

First Published in 1995book contains short reviews intended to highlight points of growing interest in mechanistic toxicology. The first section considers selected aspects of molecular mechanisms, including selectivity of toxic agents and repair processes in the nervous system, toxicity of oxygen, fibers and aflatoxins. The second section discusses the interactions of carcinogens with DNA, and other targets, and their relevance to both molecular dosimetry of exposure and development of cancer. The final part is concerned with cellular and genetic aspects and includes coverage of some of the most recent and rapidly developing problems in toxicology.

Contents

Mechanisms of Toxicity1. Aspects of Selectivity and Mechanism in NeurotoxicityW. N. Aldridge2. Injury and Repair in NeurotoxicologyMarcello Lotti3. Toxicity of OxygenDonald J. Reed4. AflatoxinsMargaret M. Manson5. Experimental Studies with FibersJ.M.G. Davis and R.C. BrownBiomonitoring and Molecular Interactions in Carcinogenesis6. Biomonitoring and Molecular Dosimetry of Genotoxic CarcinogensPeter Farmer7. The Relationship of Molecular Interactions with DNA to Cancer: Scientific DevelopmentsP.N. MageeGenetic and Cellular Aspects in Toxicology8. The Study of Genes and Gene Expression by In Situ Hybridization: A Potentially Useful Approach in ToxicologyIan Lauder9. Genetic Variation in Human and Laboratory Animal Populations and Its Implications for Toxicological Research and Human Risk AssessmentMichael F. W. Festing10. Mechanisms of Cell Death, with Particular Reference to ApoptosisGerald M. Cohen et al.11. Apoptosis: Some Aspects of Regulation and Role in CarcinogenesisRolf Schulte-Hermann