Freeze Drying of Pharmaceutical Products (Advances in Drying Science and Technology)

Fissore, Davide (EDT)/ Pisano, Roberto (EDT)/ Barresi, Antonello (EDT)

CRC Press（2019/11発売）

• 製本 Hardcover:ハードカバー版／ページ数 192 p.
• 言語 ENG
• 商品コード 9780367076801
• DDC分類 615.19

Full Description

Freeze Drying of Pharmaceutical Products provides an overview of the most recent and cutting-edge developments and technologies in the field, focusing on formulation developments and process monitoring and considering new technologies for process development.

This book contains case studies from freeze dryer manufacturers and pharmaceutical companies for readers in industry and academia. It was contributed to by lyophilization experts to create a detailed analysis of the subject matter, organically presenting recent advancements in freeze-drying research and technology. It discusses formulation design, process optimization and control, new PAT-monitoring tools, multivariate image analysis, process scale-down and development using small-scale freeze-dryers, use of CFD for equipment design, and development of continuous processes.

This book is for industry professionals, including chemical engineers and pharmaceutical scientists.

Contents

1. Formulation Design and Optimization Using Molecular Dynamics. 2. Established and Novel Excipients for Freeze-Drying of Proteins. 3. Multivariate Image Analysis: A New PAT for Freeze-Drying Monitoring. 4. Impedance Methods for Process Monitoring. 5. Innovations in Freeze-Drying Control and In-Line Optimization. 6. Process Design, Optimization and Scale-Up Using Micro Freeze-Dryers. 7. Continuous Freeze-Drying. 8. Pat for Batch and Continuous Freeze-Drying Processes. 9. Use of CFD for the Design and Optimization of Freeze-Dryers.