Cellular, Molecular, and Environmental Contribution in Cardiac Remodeling : From Lab Bench Work to its Clinical Perspective

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Cellular, Molecular, and Environmental Contribution in Cardiac Remodeling : From Lab Bench Work to its Clinical Perspective

Duttaroy, Asim K./ Mallick, Rahul

ウェブストア価格 ¥35,312（本体¥32,102）
Academic Press Inc（2024/04発売）
外貨定価 US$ 165.00
ポイント 321pt

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製本 Paperback:紙装版/ペーパーバック版／ページ数 340 p.
言語 ENG
商品コード 9780323995702
DDC分類 616.106

Full Description

Cellular, Molecular and Environmental Contribution in Cardiac Remodeling consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. The book extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise, and more.

It provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, along with its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed.

1. Cardiac remodeling: Impacts on cardiac health and disease
2. Physiological cardiac modeling: Effects of exercise and other factors
3. Prognostic elements of unfavorable cardiac remodeling
4. Growth and proliferation of cardiomyocytes: roles of energy metabolism, cell death, oxidative stress, and metabolites
5. Cardiac endothelial cells and their cross-talks with neighboring cells in cardiac remodeling
6. Pathophysiology of cardiac fibroblasts and impacts on the severity of the cardiac disease
7. Involvement of cardiac stem cells in cardiac remodeling or myocardial regeneration
8. Cardiac pericytes and cardiac remodeling
9. Macrophages in the remodeling of diseased heart
10. Inflammatory role of neutrophils in cardiac remodeling: damage vs. resolution
11. Extracellular vesicle in cardiac remodeling
12. Does endoplasmic reticulum stress break the heart?
13. Role of pattern recognition receptors in cardiac remodeling
14. Junctional adhesion molecules: their roles in integrity and functionality of the heart
15. Composition and function of ion channels and their effects in cardiac remodeling
16. Cardiokines and cardiac remodeling
17. Fatty acids: friend or foe to cardiac remodeling?
18. Comparative effects of fatty acid and glucose in cardiac remodeling
19. Vitamins, minerals, and nutraceuticals and their cardioprotective function
20. NOTCH signaling molecules: a driver of cardiac function
21. Wnt signaling: a functional modulator of the heart
22. Neuregulin-1: can it be useful to treat heart failure?
23. Semaphorins and cardiac conduction system
24. Myocardial collagen: Its role in inflammation to interstitial fibrosis
25. Myocardial contractile proteins: role in disease progression and drug discovery
26. Neurohormones and cardiac remodeling and function
27. Regulation and function of the Hippo signaling system in the cardiac pathophysiological process
28. Cardiac lymphatic system about myocardial health
29. Long non-coding RNAs and microRNAs' regulatory roles in cardiac disease: an emerging area of research
30. Artificial intelligence and cardiac remodeling: emerging ally