Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery (Woodhead Publishing Series in Biomaterials)

Chattopadhyay, Dipankar/ Orasugh, Jonathan Tersur/ Adhikari, Anjan

Woodhead Publishing（2024/05発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 672 p.
• 言語 ENG
• 商品コード 9780323991568
• DDC分類 620.11

Full Description

Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery covers fundamental aspects in the preparation of polymeric in-situ, stimuli-responsive hydrogels, including properties, characterization, chemistry, and fabrication of these hydrogels. The book will help the reader select the most appropriate material and design for the desired application. The book goes on to review applications in ophthalmic drug delivery, covering in vitro and in vivo models, animal models, preclinical testing, patents, and more. This is a must-have reference for researchers and academics in the fields of materials science, biomaterials, pharmacology and polymer science, with an interest in clinical aspects of hydrogel design and application.

Contents

Part I: Properties and Preparation
1. Introduction to polymeric in-situ forming hydrogels
2. Biopolymers for in-situ forming hydrogels: synthesis, characterization, and toxicity
3. Chemistry and applications of biopolymer stimuli-responsive in-situ gels
4. Design, engineering, and fabrication of biopolymer in-situ forming hydrogels
5. Process optimization for design and fabrication of biopolymer stimuli-responsive
hydrogels
6. Properties of biopolymeric in-situ hydrogels
7. Swelling and drug release kinetics of biopolymer in-situ forming hydrogels
8. Structural and load-bearing characteristics of biopolymer in-situ forming hydrogels
9. Functionalization of in-situ forming biopolymer hydrogels

Part II: Applications in Ophthalmic Drug Delivery
10. Eye anatomy, physiology, and ocular barriers
11. In vitro and in vivo models in ophthalmic drug delivery
12. Formulation and ocular drug delivery routes
13. Clinical indications of stimuli-responsive hydrogels in ophthalmic drug delivery
14. Natural and synthetic materials for stimuli-responsive hydrogels in ophthalmic drug delivery
15. Characteristics and kinetics of in-situ forming hydrogels in ophthalmic drug delivery
16. Cell-laden stimuli-responsive hydrogels in ophthalmic drug delivery
17. Animal models and preclinical tests for evaluation of stimuli-responsive hydrogels in ophthalmic drug delivery
18. Biopolymer-based in-situ forming hydrogels: from laboratory to practical application
19. Commercially available stimuli-responsive hydrogels for ophthalmic drug delivery
20. Advantages and challenges of biopolymer in-situ hydrogels for ophthalmic drug delivery
21. Patents for biopolymer in-situ hydrogels for ophthalmic drug delivery