Lantibiotics as Alternative Therapeutics (Advances in Biotechnology and Bioengineering)

Joshi, Sanket (EDT)/ Kar, Rajiv K. (EDT)/ Lahiri, Dibyajit (EDT)

Academic Press Inc（2023/03発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 522 p.
• 言語 ENG
• 商品コード 9780323991414
• DDC分類 615.7922

Full Description

Lantibiotics as Alternative Therapeutics explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections.

Novel compounds exhibit different modes of action to the currently used mechanism of therapeutics in order to combat against the resistant organisms. Lantibiotics hold considerable potential as a consequence of their unusual structure, unique mechanisms of action and their potency against multi-drug resistant bacteria. This book will be useful for pharmaceutical industry scientists and researchers in microbial and biomedical research as well as graduate and advanced students in microbiology, medical biotechnology, health, and pharmaceutical sciences.

Contents

1. Genetics of the development of antibiotic and multi-drug resistance
2. Antimicrobial peptides and the potent mechanism of action
3. Lantibiotics and Gene regulation
4. Biosynthesis of Lantibiotics
5. Optimizations in the productions of Lantibiotics and Scale-Up
6. Analytical Techniques in Identifying & Purifying the proteins
7. Development of Recombinant Lantibiotics and their Potent Uses
8. Mechanism of Action of the Lantibiotics on the Multi-Drug Resistant Organism
9. Mechanism of inhibiting Biofilm associated Chronic Infections by Lantibiotics
10. Lantibiotics & Its Role in Food Preservation
11. In-Silico studies of the Interaction of Lantibiotics with Virulent Proteins
12. Insights at the atomistic resolution of Lantibiotics using Multiscale Simulations
13. Case studies: Applications of such novel drugs
14. Recent updates in understanding of molecular genetics of lantibiotics production
15. In silico molecular modelling approach for better designing and applications
16. Marine microbes as a potential source of novel drugs
17. Combinations of nano-bio molecules as next generation antimicrobial agents