Full Description
At the heart of precision medicine lies one concept missing from modern medicine - the unique genetic and biochemical make-up of each individual patient. Implementation of Personalized Precision Medicine: Expanding the Clinical Vision towards Prevention, Early Detection, and Precision Treatment of Disease to Drive Extended Healthspan establishes a landscape of precision medicine geared towards implementation of fully personalized approaches within precision medicine to facilitate prevention and early detection of age-related disease in each individual. This reference details how these lofty goals are now achievable with the science of today and tomorrow and provides the context, thought process and beginning blueprint to guide researchers and clinicians in more effectively considering the prevention and treatment of complex chronic disease.
Uniquely organized, this reference provides insight into creating fully personalized precision medical treatments. Chapters include conventionally considered data such as genetic inherited risk, current epigenetic modifications, and current biochemical markers but also include less conventional food for thought such as microbiome, mitochondrial function, and dna repair. This provocative landscape makes this reference a valuable addition to the literature expanding precision medicine towards personalized chronic disease prevention and treatment.
Contents
1. Epigenetics/methylation
2. Polygenic Risk Scores: A conceptual overview to add PRS to your clinical toolbox
3. The Proteomics Revolution: Forging a New Path to Personalized Healthcare
4. Pharmacogenetic Implementation
5. Molecular Imaging
6. Early quantum computing applications on the path towards precision medicine
7. Gene Therapy: State of the Art Precision Medicine
8. Precision Mitochondrial Medicine: Uncovering Pathways Across Diverse Diseases
9. Antigen-specific immunotherapy: The ultimate precision medicine for treatment of autoimmune diseases
10. The Future of Precision Diabetes: Digital Twin
11. Precision Oncology: Indications and Challenges in the Implementation of High-throughput Sequencing in Clinical Practice
12. Bringing "Precision" to Psychiatry: Challenges and Promises
13. Precision Medicine in Cardiovascular Disease
14. Precision Bone Health: A WGS Look at Bone Density
15. Functional Nutrigenomics: A Personalized Shift in Treating Inflammation
16. Regulating Ferroptosis: Towards Precision Treatment of Dysregulated Cell Death
17. Precision Medicine for Brain Health and Prevention of Neurodegenerative/Neurocognitive Decline
18. Gut Microbiome in Personalized Precision Medicine
19. The Exposome and Detoxification: New Tools for Precision Health
20. Unraveling Time: Longevity and DNA Repair Mechanisms
21. Considering Ethics in Precision Medicine
22. Personomics: The Personalization of Precision Medicine
