Full Description
Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics: Recent and Future Trends in Pharmaceutics, Volume Two explores aspects of pharmaceutics with an original approach that focuses on technology, novelties and future trends. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. Readers will find practical information for conducting research in pharmaceutics that is ideal for researchers in academia and industry as well as advanced graduate students in pharmaceutics.
In addition, the book discusses the most recent developments in biopharmaceutics, including important and exciting areas such as solubility of drugs, pharmaceutical granulation, routes of drug administration, drug absorption, bioavailability and bioequivalence.
Contents
Section I: Physico-chemical aspects of dosage forms
1. Physico-chemical factors influencing drug degradation
2. Stability and accelerated stability studies of dosage forms
3. Solubility of drugs
4. Drug dissolution studies of pharmaceutical formulations
5. Pharmaceutical granulation: Engineering perspective and futuristic trends
6. Tablet compression and consolidation: Theory and applications
Section II: Biopharmaceutics
7. Introduction to Biopharmaceutics
8. Gastrointestinal absorption of drugs
9. Routes of drug administration and their impact in biopharmaceutics
10. Drug elimination and renal excretion of drugs
11. Membrane transport and permeation of drugs
12. Factors affecting drug absorption and disposition
13. Bioavailability and bioequivalence
14. Contribution of biopharmaceutics and pharmacokinetics to improve drug therapy
15. Dosage regimen
16. Multicompartment models
17. Nonlinear pharmacokinetics
18. Computer-aided biopharmaceutical model development
19. Computer simulations in pharmacokinetics
20. WHO and ICH Guidelines for 'Good Manufacturing Practices'
21. Pilot plant scale up techniques in pharmaceutical product development
22. Advances in solid dosage forms
