Full Description
Vaccinology and Methods in Vaccine Research is a combination of cutting-edge methodologies, experimental approaches and literature reviews. The book covers all aspects of vaccine development, including basic immunology (focusing on the stimulation of adaptive immunity, which is required for vaccine efficacy), approaches to vaccine design and target validation, vaccine biomanufacturer and clinical development. Existing vaccinology resources are theoretical reference books, whereas this book provides a practical handbook for use in the research lab and classroom by those working in vaccinology and training others in the field.
It is authored and edited by scientists actively engaged in vaccine research and development for day-to-day teaching/methodological advice.
Contents
1. Immunology and the Concept of Vaccination
Rebecca Chukwuanukwu, A. Ehiaghe, A. Rowaiye and Angus Nnamdi Oli
2. Vaccine Types and Reverse Vaccinology
A. Rowaiye and Angus Nnamdi Oli
3. Dendritic Cells as Vaccine Targets
P. Aondona, F. Iseghohi, A. Rowaiye and Angus Nnamdi Oli
4. Vaccine Development: From the Laboratory to the Field
Nana Efua Andoh and Linda Onyeka Anagu
5. Immunopeptidomics for the Identification of T cell Vaccine Targets
P. Bettencourt and C. Barbosa
6. Virus Like Particle Vaccines
Ahmed M. Salman, Ekta Mukhopadhyay and Adrian Hill
7. Approaches to Cancer Vaccination
Ezinne Janefrances Nwonu
8. Vaccines against SARS-CoV-2
K. Ewer and Andrés Noé
9. Adjuvants, Immunomodulators and Adaptogens
Anita Milicic, M. Ugwu, Sabina Górska, Agnieszka Razim, M. Luchner, Slavcho Mrenoshki, H. Kefei, G. Corby, A. Thakur, Sveinbjorn Gizurarson, J. Fergusson, Dennis Christensen, S. Ercelen, S. Longet, B. Morein, E. Lindblad and S. Reinke
10. GMP Manufacture and Quality Control Chapter
Rebecca Ashfield
11. Testing Vaccines: Essential Steps in Clinical Trial Design
Julia Marshall
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