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Full Description
This volume focuses on the major aspects of post-transcriptional mRNA processing in the nucleus of eukaryotic cells. Each of the described mRNA reactions is required for proper gene expression and can also serve as a control point for regulating the expression of many genes, for example during embryonic development or in different cell types. This book is intended for postgraduates, post-doctoral researchers, and academic staff in eukaryotic molecular biology.
Contents
1: RNA-catalysed RNA processing. 2: Nuclear organization of pre-mRNA splicing factors and substrates. 3: The packaging of pre-mRNA. 4: Spliceosome assembly. 5: snRNP structure and function. 6: Mammalian pre-mRNA splicing factors. 7: Pre-mRNA splicing factors in the yeast Saccharomyces cerevisiae. 8: Alternative pre-mRNA splicing. 9: Capping, methylation, and 3'-end formation of pre-mRNA. 10: Trans-splicing. 11: mRNA editing