- ホーム
- > 洋書
- > 英文書
- > Science / Mathematics
Full Description
Lipoproteins play an important role in maintaining the normal distribution of lipids in the body and in the transport of lipophilic comounds. They are also implicated, however, in some of the major diseases of the Western world including atherosclerosis, heart disease, and stroke, which has led to a dramatic proliferation of lipoprotein research. The focus of this volume is on the analysis of the biological activity of lipoproteins. It contains a selection of chapters which provide detailed protocols for preparing and separating different lipoproteins, followed by methods for studying their metabolism, activity in different tissues and interactions with receptors. This work is designed to serve as a useful manual for biomedical scientists studying these compounds including those interested in their role in diseases of the circulatory system.
Contents
Lipoprotein separation and analysis for clinical studies, M.I. Mackness and Paul N. Durrington; qualitative and quantitative separation of human apolipoproteins, H. Dieplinger et al; immunological methods for studying and quantifying lipoproteins and apolipoproteins, R.W. Milne et al; the separation and analysis of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) subfractions, E.R. Skinner; lipoprotein turnover and metabolism, A. Gaw et al; lipoprotein-receptor interactions, K.S. Arnold et al; methods for the assay of enzymes relevant to lipoprotein metabolism - assay of lipoprotein lipase and hepatic lipase, G. Bengtsson-Olivecrona and T. Olivecrona, cholesterol esterifying enzymes - lecithin:cholesterol acyltransferase (LCAT) and acylcoenzyme A:cholesterol acyltransferase (ACAT), M.P.T. Gillett and J.S. Owen, assay of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, P.A. Wilce and P.A. Kroon; analysis of tissue lipoproteins, R.E. Pitas and R.W. Mahley.
