Limiting Dilution Analysis of Cells of the Immune System (2ND)

Limiting Dilution Analysis of Cells of the Immune System (2ND)

  • ただいまウェブストアではご注文を受け付けておりません。 ⇒古書を探す
  • 製本 Hardcover:ハードカバー版/ページ数 300 p.
  • 言語 ENG
  • 商品コード 9780198501282
  • DDC分類 571.9619

Full Description

This edition is a treatise on the rationale of limiting dilution analysis (LDA). LDA has evolved from its previous role as a basic research laboratory tool in virology and immunology to one pertaining to many different research disciplines and to clinical applications. New methodologies (such as PCR, confocal microscopy, in situ hybridization) have emerged, with the result that single-cell assays can now be performed on a more defined basis, and the quantitation of cells and their precursors is now more accessible to the limiting dilution approach. This book includes both detailed mathematical derivations and methodological descriptions so that the uninitiated scientist can set up and evaluate limiting dilution experiments without further instruction. It also describes particular examples of how LDA is being used to determine clinical practice.

Contents

Preface; From Poisson to Schrodinger; Theory; Statistics; Models of limiting dilution analysis; Models of clonal partition analysis; Exemplary experimental systems and titration protocols; Lymphocyte functions resolved by LDA: A perspective; The clinical potential of LDA; LDA program; Simulation experiments

最近チェックした商品