基本説明
Written by the leading experts in autism research, this text provides a summary of all the current knowledge related to the behavioral, experiential, and biomedical features of the autism spectrum disorders.
Full Description
Autism is an emerging area of basic and clinical research, and has only recently been recognized as a major topic in biomedical research. Approximately 1 in 100 children are diagnosed as autistic, so it is also an intense growth area in behavioral and educational treatments. Financial resources have begun to be raised for more comprehensive research and an increasing number of scientists are becoming involved in autism research. In many respects, autism has become a model for conducting translational research on a psychiatric disorder. This text provides a comprehensive summary of all current knowledge related to the behavioral, experiential, and biomedical features of the autism spectrum disorders including major behavioral and cognitive syndromology, common co-morbid conditions, neuropathology, neuroimmunology, and other neurological correlates such as seizures, allergy and immunology, gastroenterology, infectious disease, and epidemiology.
Edited by three leading researchers, this volume contains over 80 chapters and nine shorter commentaries by thought leaders in the field, making the book a virtual "who's who" of autism research. This carefully developed book is a comprehensive and authoritative reference for what we know in this area as well as a guidepost for the next several years in all areas of autism research.
Contents
INTRODUCTION: AUTISM TURNS 65: A NEUROLOGIST'S BIRD'S EYE VIEW; ISABELLE RAPIN; SECTION I: HISTORICAL PERSPECTIVE, DIAGNOSIS AND CLASSIFICATION, AND EPIDEMIOLOGY; MICHAEL RUTTER; KATHERINE GOTHAM, SOMER L. BISHOP, AND CATHERINE LORD; AMI KLIN; SALLY OZONOFF, KELLY HEUNG, AND MEAGAN THOMPSON; ROY RICHARD GRINKER, MARSHALYN YEARGIN-ALLSOPP, AND COLEEN BOYLE; COMMENTARY: ISSUES IN THE CLASSIFICATION OF PERVASIVE DEVELOPMENTAL DISORDERS; PATRICK BOLTON; SECTION II: CORE FEATURES AND DEVELOPMENTAL TRAJECTORIES; PETER MUNDY; HELEN TAGER-FLUSBERG, LISA EDELSON, AND RHIANNON LUYSTER; WOUTER B. GROEN AND JAN K. BUITELAAR; JAMES W. BODFISH; REBECCA J. LANDA; TONY CHARMAN; MARSHA MAILICK SELTZER, JAN S. GREENBERG, JULIE LOUNDS TAYLOR, LEANN SMITH, GAEL I. ORSMOND, ANNA ESBENSEN, AND JINKUK HONG; COMMENTARY: ISSUES IN DEFINING THE CORE FEATURES OF AUTISM THROUGH THE LIFESPAN BY KATHERINE A. LOVELAND; SECTION III: PSYCHIATRIC AND MEDICAL CO-MORBIDITIES; ELISABETH M. DYKENS AND MIRIAM LENSE; BONNIE P. TAYLOR AND ERIC HOLLANDER; SUMA JACOB, ANGELI LANDEROS-WEISENBERGER, AND JAMES F. LECKMAN; ANGELA M. REIERSEN AND RICHARD D. TODD; J. BRUCE TOMBLIN, KARLA MCGREGOR, AND ALLISON BEAN; PETER SZATMARI AND BETH MCCONNELL; LINDSEY STERLING, ANNIE MCLAUGHLIN, AND BRYAN H. KING; MATTHEW W. MOSCONI, YUKARI TAKARAE, AND JOHN A. SWEENEY; ROBERTO TUCHMAN; PAULA GOINES, ANDREW ZIMMERMAN, PAUL ASHWOOD, AND JUDY VAN DE WATER; TIMOTHY BUIE; ANNE E. PORTER AND DANIEL G. GLAZE; COMMENTARY: AUTISM AS A MEDICAL DISORDER BY CHRISTOPHER GILLBERG; SECTION IV: BROADER AUTISM PHENOTYPE; MOLLY LOSH, RALPH ADOLPHS, AND JOSEPH PIVEN; JANET E. LAINHART AND NICHOLAS LANGE; JOHN N. CONSTANTINO; COMMENTARY: THE BROADER AUTISM PHENOTYPE: IMPLICATIONS FOR RESEARCH AND CLINICAL PRACTICE BY JEREMY R. PARR, KERSTIN WITTEMEYER, AND ANN S. LE COUTEUR; SECTION V: NEUROBIOLOGY; JOHN L. R. RUBENSTEIN; CYNTHIA M. SCHUMANN, STEVEN C. NOCTOR, AND DAVID G. AMARAL; DIANE C. CHUGANI; STEPHEN R. DAGER, NEVA M. CORRIGAN, TODD RICHARDS, AND DENNIS SHAW; MEERA E. MODI AND LARRY J. YOUNG; ERIC COURCHESNE, SARA JANE WEBB, AND CYNDI SCHUMANN; NANCY J. MINSHEW, K. SUZANNE SCHERF, MARLENE BEHRMANN, AND KATHERINE HUMPHREYS; SARA JANE WEBB, RAPHAEL BERNIER, KAREN BURNER, AND MICHAEL MURIAS; COMMENTARY: TOWARD A NEUROBIOLOGY OF AUTISM BY PAT LEVITT; SECTION VI: ETIOLOGY: GENETICS; JANINE A. LAMB; RITA M. CANTOR; JUDITH H. MILES; HANDE KAYMAKCALAN AND MATTHEW W. STATE; RICHARD PERSON, XINNA ZHANG, SOEUN KIM, MARWAN SHINAWI, AND ARTHUR L. BEAUDET; KAROLA REHNSTROM AND LEENA PELTONEN; ERIC M. MORROW AND CHRISTOPHER A. WALSH; JEFFREY L. NEUL; RANDI J. HAGERMAN, VIVIEN NARCISA, AND PAUL J. HAGERMAN; COMMENTARY: AUTISM GENETICS AND GENOMICS: A BRIEF OVERVIEW AND SYNTHESIS BY DANIEL H. GESCHWIND; SECTION VII ETIOLOGY: ENVIRONMENTAL FACTORS; IRVA HERTZ-PICCIOTTO; PATRICIA M. RODIER; MARK A. CORRALES AND MARTHA R. HERBERT; SECTION VIII: ANIMAL MODELS AND THEORETICAL PERSPECTIVES; ALICIA BLAKER, GIANLUCA DERIENZO, AND HAZEL SIVE; MU YANG, MARIA LUISA SCATTONI, KATHRYN K. CHADMAN, JILL L. SILVERMAN, AND JACQUELINE N. CRAWLEY; ELAINE HSIAO, CATHERINE BREGERE, NATALIA MALKOVA, AND PAUL H. PATTERSON; MELISSA D. BAUMAN AND DAVID G. AMARAL; RAJESH K. KANA AND MARCEL ADAM JUST; SIMON BARON-COHEN, BONNIE AUYEUNG, EMMA ASHWIN, AND REBECCA KNICKMEYER; MARCO IACOBONI; KEITH J. YODER AND MATTHEW K. BELMONTE; COMMENTARY: TRANSLATION BETWEEN DIFFERENT TYPES OF MODEL BY FRANCESCA HAPPE; SECTION IX: TREATMENT APPROACHES; TRISTRAM SMITH; LAURA SCHREIBMAN AND BROOKE INGERSOLL; STANLEY I. GREENSPAN AND SERENA WIEDER; SALLY J. ROGERS AND KATHERINE WALLACE; LYNN KERN KOEGEL, ROSY M. FREDEEN, ROBERT L. KOEGEL, AND C. ENJEY LIN; LINN WAKEFORD AND GRACE T. BARANEK; MARJORIE H. CHARLOP, ALISSA L. GREENBERG, AND GINA T. CHANG; EDWARD G. CARR; CONNIE KASARI AND JILL LOCKE; ROBIN GABRIELS; ANNETTE ESTES, VANESSA HUS, AND LAUREN ELDER; KELLY BLANKENSHIP, CRAIG A. ERICKSON, KIMBERLY A. STIGLER, DAVID J. POSEY, AND CHRISTOPHER J. MCDOUGLE; MARGARET L. BAUMAN; SUSAN L. HYMAN AND SUSAN E. LEVY; DILJA D. KRUEGER AND MARK F. BEAR; COMMENTARY: FUTURE DIRECTIONS IN THE TREATMENT OF AUTISM SPECTRUM DISORDERS BY EVDOKIA ANAGNOSTOU, MARK F. BEAR, AND GERALDINE DAWSON; SECTION X: BEST PRACTICES IN THE DIAGNOSIS AND TREATMENT OF AUTISM; ZACHARY WARREN AND WENDY L. STONE; DANIEL L. COURY; KARA HUME AND SAMUEL L. ODOM; JAMES T. MCCRACKEN; MARY CATHERINE ARANDA AND SARAH J. SPENCE; COMMENTARY: BIOETHICAL CONSIDERATIONS IN AUTISM RESEARCH AND TRANSLATION: PRESENT AND FUTURE BY HOLLY K. TABOR; SECTION XI: PUBLIC POLICY; DJESIKA AMENDAH, SCOTT D. GROSSE, GEORGINA PEACOCK, AND DAVID S. MANDELL; THOMAS INSEL AND SUSAN A. DANIELS; PETER H. BELL AND CRAIG SNYDER; TEMPLE GRANDIN
