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Full Description
The fields of molecular evolution, genome evolution, and evolutionary genetics are now well-established. Remarkably, however, although all evolutionary modifications begin at the cellular level, and despite the advances made in cell biology and microbiology over the past few decades, there is as yet no recognised discipline of evolutionary cell biology. The goal of this book is to help establish the foundations for this emerging field. Its principal aims are twofold: firstly, to promote an understanding among evolutionary biologists as to why the cellular details matter if we are to understand the mechanisms of evolution; secondly, to make clear to non-evolutionary biologists - cell biologists in particular - that evolution is not just a matter of natural selection and optimization, but a process whose reach depends on other population genetic features such as mutation, recombination, and random genetic drift.
Although there are many excellent books on cell biology, microbiology, and biophysics, almost no attention is given to evolution. Likewise, although there are numerous evolutionary biology books on the market, none of them gives more than passing attention to details at the cellular level. Thus Evolutionary Cell Biology is genuinely novel, offering a broader understanding of evolutionary processes and an appreciation for the many interesting problems that remain to be solved at the cellular and subcellular levels.
This advanced textbook is aimed at both cell biologists and evolutionary biologists. It will be accessible to upper-level undergraduates in biology, and certainly to graduate students in all areas of the life sciences. Professionals from a wide range of fields - cell biology, microbiology, evolution, biophysics, biochemistry, and mathematics - will be exposed to entirely new ideas not traditionally covered in their primary fields of expertise.
Contents
Preface
Part I: Introduction
1: Evolutionary Cell Biology
2: The Origin of Cells
3: The Major Lines of Descent
Part II: The Genetic Mechanisms of Evolution
4: The Population-genetic Environment
5: Evolution as a Population-genetic Process
6: Evolution of Cellular Complexity
Part III: Basic Cellular Features
7: The Cellular Environment
8: Evolutionary Scaling Laws in Cell Biology
9: Cell Growth and Division
10: The Cell Life Cycle
11: Cellular Senescence
Part IV: Structural Evolution
12: The Protein World
13: Multimerization
14: Protein Management
15: Lipids and Membranes
16: Cytoskeleton, Cell Shape, and Motility
Part V: Energetics and Metabolism
17: The Costs of Cellular Features
18: Resource Acquisition and Homeostasis
19: Enzymes and Metabolic Pathways
Part VI: Information Processing
20: Intracellular Errors
21: Intracellular Communication: Transcription
22: Environmental Sensing and Extracellular Communication
Part VII: Organismal Complexity
23: Endosymbiosis
24: Origins of Organismal Complexity
