Full Description
Handbook on the Toxicology of Metals, Fifth Edition, Volume I: General Considerations is the first volume of a two-volume work that gives an overview and covers topics of general importance including reviews of various health effects of trace metals. The book emphasizes toxic effects in humans, along with discussions on the toxic effects of animals and biological systems in vitro when relevant. The book has been systematically updated with the latest studies and advances in technology and contains several new chapters. As a multidisciplinary resource that integrates both human and environmental toxicology, the book is a comprehensive and valuable reference for toxicologists, physicians, pharmacologists, and environmental scientists in the fields of environmental, occupational and public health.
Contents
1. Toxicology of metals: Overview, definitions, concepts, and trends
2. General chemistry of metals, sampling, analytical methods, and speciation
3. Exposure, dose, and toxicokinetics of metals
4. Toxicity of metal and metal oxide nanoparticles
5. Toxicity of metals released from implanted medical devices
6. Metals and air pollution
7. Toxic metals in food
8. Interaction of toxic metals with the gut microbiome
9. Biological monitoring of metals and biomarkers
10. Computational modeling and dosimetry of metals
11. Selected molecular mechanisms of metal toxicity and carcinogenicity
12. Effects of metals on extracellular vesicle signaling
13. General considerations of dose-effect and dose-response relationships
14. Interactions and mixtures in metal toxicology
15. Gene-Environment interactions and metal toxicity
16. Epidemiological approaches to metal toxicology
17. Essential metals: assessing risks from deficiency and toxicity
18. The interaction of metals and the skin: the good, bad, and the ugly
19. Metals and the respiratory tract
20. Neurotoxicology of metals
21. Metals and cardiovascular disease
22. Renal effects of exposure to metals
23. Carcinogenicity of metal compounds
24. Immunotoxicology of metals
25. Effects of metallic elements on reproduction and development
26. Ecotoxicology of metals-sources, transport, and effects on the ecosystem
27. Risk assessment for metal exposures
28. Diagnosis and treatment of metal poisoning general aspects
29. Principles for prevention of the toxic effects of metals
30. Metal toxicology in low-income and lower-middle-income countries
