Full Description
Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states.
This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful.
Contents
Part 1: Synthesis and characterization of NP for drug delivery1. Nanoparticles: Recent state-of-art and prospective challenges2. Fabrication, process technologies and challenges in development of nanoparticles3. In vitro and physicochemical characterization of nanoparticles4. Surface-engineering of nanoparticles for imparting multifuntionality5. Biofate and cellular interactions of nanoparticles6. Pharmacokinetics and in vivo evaluation of nanoparticles
Part 2: Application of Nanoparticles in Drug Delivery7. Biodegradable polymeric nanoparticles for sustained drug delivery8. Lipidic nanoparticles with improved biopharmaceutical attributes9. Protein-based nanoparticles for drug delivery10. Gold and silver nanoparticles for drug delivery11. Mesoporous silica and silicates nanoparticles for drug delivery12. Targeted nanosuspensions for improved therapeutics13. SPIONS as therapeutic and diagnostic agents14. Bio-inspired nanoparticles/exosomes vesicles as drug delivery vehicles
Part 3: Environmental and Regulatory Aspects14. Regulatory pathways and federal perspectives on nanoparticles15. Environmental hazards associated with nanoparticles16. Biological toxicity of nanoparticles
