Full Description
Antioxidants Effects in Health: The Bright and the Dark Side examines the role that antioxidants play in a variety of health and disease situations. The book discusses antioxidants' historical evolution, their oxidative stress, and contains a detailed approach of 1) endogenous antioxidants, including endogenous sources, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; 2) synthetic antioxidants, including sources, chemistry, bioavailability, legal status, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; and 3) natural antioxidants, including sources, chemistry, bioavailability, mechanisms of action, possible prooxidant activity; beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies. Throughout the boo, the relationship of antioxidants with different beneficial and detrimental effects are examined, and the current controversies and future perspectives are addressed and explored. Antioxidants Effects in Health: The Bright and the Dark Side evaluates the current scientific evidence on antioxidant topics, focusing on endogenous antioxidants, naturally occurring antioxidants and synthetic antioxidants. It will be a helpful resource for pharmaceutical scientists, health professionals, those studying natural chemistry, phytochemistry, pharmacognosy, natural product synthesis, and experts in formulation of herbal and natural pharmaceuticals.
Contents
Part 1. Introduction
1. Evolution of antioxidants over times
2. The oxidative stress: Causes, free radicals, targets, mechanisms, affected organs, effects, indicators
3. Food autooxidation
Part 2. Endogenous antioxidants
4. Alpha lipoic acid
5. Bilirubin
6. Catalase
7. Coenzyme Q
8. Ferritin
9. Glucose-6-phosphate-dehydrogenase
10. Glutathione peroxidise
11. Glutathione reductase
12. Gluthathione
13. Superoxide dismutase
14. Uric acid
Part 3. Synthetic antioxidants: bright and the dark side
15. Ascorbyl palmitate
16. Butylated hydroxyanisole (BHA)
17. Butylated hydroxytoluene (BHT)
18. Erythorbic acid (D-ascorbic acid)
19. Nordihydroguaiaretic acid (NDGA)
20. Octyl gallate (OG)
21. Propyl gallate (PG)
22. tert-butylhydroxyquinone (TBHQ)
Part 4. Natural occurring antioxidants: bright and the dark side
23. Amino acids
24. Carnosine
25. Carnosol
26. Carotenoids (xanthophylls and carotenes)
27. Citric acid
28. Coenzyme Q
29. Curcumin
30. Flavonoids
31. Lecithin
32. Lignans
33. Organosulfur compounds( allyl sulphide, indoles)
34. Phenolic acids
35. Phytic acid
36. Protein hydrolysates
37. Saponins
38. Selenium
39. Sterols
40. Stilbenes
41. Tartaric acid
42. Turmeric
43. Uric acid
44. Vanillin
45. Vitamin A (retinol)
46. Vitamin C
47. Vitamin E (tocopherols and tocotrienols)
48. Vitamin K
49. Zinc
Part 5. Antioxidants and diseases: Beneficial and detrimental effects
50. Antioxidants and cancer
51. Antioxidants and cardiovascular diseases
52. Antioxidants and cataracts/ age-related macular degeneration
53. Antioxidants and cognitive decline in elderly
54. Antioxidants and dentistry
55. Antioxidants and diabetes
56. Antioxidants and gastric lesions
57. Antioxidants and immune functions
58. Antioxidants and infertility
59. Antioxidants and liver diseases
60. Antioxidants and neurological disorders and psychiatric disorders
61. Antioxidants and respiratory diseases
62. Antioxidants and viral diseases
Part 6: Actual and future perspectives on antioxidants
63. Duality: antioxidants/prooxidants
64. Food and food supplements antioxidants: Targets in human antioxidant system and effects on the production of endogenous antioxidants
65. Concluding remarks and future perspectives
