Full Description
Toxicology: Oxidative Stress and Dietary Antioxidants examines the nature of oxidative stress as a consequence of exposure to toxins and how antioxidant approaches can mitigate the impact of toxicant exposures. Sections covers the basic biology of oxidative stress, from molecular biology, to physiological pathology, mechanisms of action of specific toxicants, metals and other chemicals/drugs, and antioxidant approaches and therapies for toxic exposures. With contributions from an international group of experts, useful summary sections, a dictionary of terms, and applications to other areas of toxicology, this book is an informative, consolidated reference that helps bridge the interrelationship between toxicology, oxidative stress and antioxidants.
Contents
PART 1 TOXICOLOGY AND OXIDATIVE STRESS
AGRICULTURAL AND INDUSTRIAL CHEMICALS
1. Organophosphate pesticides toxicity, liver cells and linking oxidative stress
2. Organophosphate insecticide toxicity and linking oxidative stress
3. Organochlorine pesticide toxicity and linking oxidative stress
4. Paraquat and reactive oxygen species damage
5. Atrazine and oxidative stress
6. Fungicide and oxidative stress: a focus on Ziram
7. Dioxins and oxidative stress
8. Polyaromatic hydrocarbons
9. Oxidative stress and neonicotinoid insecticides
METALS
10. Lead toxicity and linking oxidative stress
11. Cadmium toxicity and linking oxidative stress (author to link in human aspects)
12. Mercury toxicity and linking oxidative stress as indicated by malondialdehyde
13. Chromium toxicity and linking oxidative stress
14. Arsenic toxicity and linking oxidative damage
15. Rare earth element toxicity and genes in linking oxidative stress pathways
DRUGS, FOOD DERIVED, CHEMICALS AND OTHER AGENTS
16. Asbestos fibers and oxidative stress
17. Anticancer agents and apoptotic cell death: linking antioxidant genes
18. Chlorine toxicity, oxidative stress and impact on isoprostanes
19. Ionic liquids as toxic agents and effects reactive oxygen species
20. 1,2-Dichloropropanetoxicity and reactive oxygen species
21. Aflatoxin B1 toxicity and the role of oxidative stress
22. Acetaminophen toxicity: the role of free radical mediated injury
23. Alcohol toxicity and the role of oxidative stress
24. Air pollution and pulmonary oxidative stress
25. Radiation and oxidative stress
26. Statins and oxidative stress with statins
PART 2 ANTIOXIDANTS AND TOXICOLOGY
AGRICULTURAL AND INDUSTRIAL CHEMICALS
27. An overview of antioxidants
28. Garlic extract and protection in malathion induced damage: facets of oxidative stress
29. Laurocerasus officinalis roem. (cherry laurel) fruit and protection against organophosphate insecticides
30. Resveratrol and protection in malathion-induced oxidative stress
METALS
31. Vitamin C and protection against arsenic
32. Fragaria ananassa and protection against cadmium toxicity
33. Citicoline as a nutraceutical and protection in metal poisoning
34. Acai fruit (Euterpe oleracea) and protection in mercury related oxidative stress
35. Antioxidant N-acetyl-l-cysteine in chromium protection
36. Nigella sativa seeds in lead related oxidative stress
37. Catechin and protection in cadmium toxicity
38. Kolaviron (KV) as an antioxidant: modelling arsenite toxicity
DRUGS, FOOD DERIVED, CHEMICALS AND OTHER AGENTS
39. Moringa oleifera leaf extract and acetaminophen protection
40. All-trans-retinoic acid and protection against renal toxicant p-aminophenol
41. Rhus tripartita extracts and ethanol-induced toxicity: glutathione-S-transferases and beyond
GENERAL ASPECTS
42. Antioxidants in Cynara scolymus and applications to toxicological sciences
43. Antioxidants in Crataegus Monogyna L flowers and applications to toxicological sciences
44. Nutrient based RiduROS and use in oxidant stress protection in radiation
45. Vernonia amygdalina (Del.) as an antioxidant in toxic injury
