Full Description
Gastroparesis: Pathophysiology, Clinical Presentation, Diagnosis and Treatment is a reference book providing a centralized source of data on gastroparesis collected over the last decade. Contents include the pathophysiology, clinical presentation, diagnostic recommendations and treatment options for gastroparesis. The reference is split into broad subsections, with the strategy of first focusing on the key features of the disease and then turning to controversies, recent developments, patient support resources, the spectrum of treatment - including medical and surgical - and future directions.
Chapters will include coverage of important topics like autonomic neuropathy, the brain-gut axis, potential pathophysiological advances at the cellular level, diagnostic and therapeutic options specifically targeted at the pylorus, and the evaluation of the female predominance in gastroparesis. This is a must-have resource for scientists looking to find the next step in their research as well as healthcare professionals ranging from Gastroenterologists to Internists, Surgeons, Nutritionists, Psychiatrists, and Psychologists, Residents and Medical Students who struggle with how to optimally take care of their gastroparetic patients.
Contents
I. Introduction & clinical presentation
1. Historical perspectives on gastric motility and gastroparesis
2. Epidemiology of gastroparesis
3. Clinical presentations of gastroparesis
4. Natural history of patients with gastroparesis
II. Pathophysiology
5. Gastric dysmotility at the organ level in gastroparesis
6. Cellular pathogenesis of gastroparesis
7. Sensory dysfunction in gastroparesis
8. Pathology of gastroparesis: ICC, enteric neurons and fibrosis
9. Gastroparesis and the brain-gut axis
10. Autonomic neuropathies and gastroparesis
III. Diagnostic considerations
11. Gastric emptying scintigraphy
12. The use of wireless motility capsule in the diagnosis and monitoring of gastroparesis
13. Breath tests for the assessment of gastroparesis
14. Magnetic resonance imaging for gastric motility and function
15. Electrogastrography for suspected gastroparesis
16. Antroduodenal manometry for the evaluation of patients with suspected gastroparesis
17. Ancillary testing including barostat, SPECT, and satiety testing
IV. Clinical subsets
18. Diabetic gastroparesis
19. Postsurgical gastroparesis
20. Idiopathic gastroparesis
21. Gastroparesis from other causes
22. Pediatric gastroparesis
V. Therapeutic considerations
23. Dietary therapy for gastroparesis
24. Prokinetic agents for gastroparesis
25. Antiemetic therapy for gastroparesis
26. Abdominal pain in gastroparesis: Prevalence, potential causes and management
27. Psychiatric aspects of gastroparesis
28. Alternative, complementary medicine and cannabinoids for gastroparesis
29. Enteric tube placement for gastroparesis: Gastrostomy, gastrojejunostomy and jejunostomy
30. Gastric electrical stimulation for gastroparesis
31. Surgical management of gastroparesis
VI. Controversies & new developments
32. Studies from the NIH Gastroparesis Clinical Research Consortium: Towards improving our understanding and treatment of gastroparesis
33. Evaluating response in gastroparesis: Patient reported outcome measures and survey
34. The pyloric revolution: Patient selection
35. Endoscopic full-thickness gastric biopsy: Ready for prime time?
36. Distinguishing between functional dyspepsia and gastroparesis: Does it matter?
37. Female predominance in gastroparesis
38. A brief history and future directions of permanent, temporary, and endoscopic GES
39. Cell transplantation for gastroparesis
40. A vision of the future for gastroparesis
41. Resources for the gastroparesis patient
