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Full Description
Precision Medicine in Pediatric Health is an invaluable resource on state-of-the-art tools, technologies and social and ethical issues involved in fully realizing precision medicine in new pediatric research and healthcare. The book adopts a holistic approach that is grounded in key learning points and practical case studies of interest to interdisciplinary teams of researchers and clinicians working in pediatrics. Chapters provide a thorough introduction to basic principles of precision medicine, its growing role in research and clinical care, relevant technologies and digital health. From there, the book examines best practices and offers support for implementing precision medicine in research and clinical settings.Chapters are devoted to varying specialties, such as prenatal and fetal health, oncology, cardiology, neurology, rare diseases, developmental disorders, and precision therapeutics, including small molecule and gene and cell-based therapies. These sections are followed by a close look at ethical, legal and social implications of precision medicine in pediatrics, patient perspectives and next steps in research and clinical translation.
Contents
1. Introduction to Precision Medicine
SECTION 1: Technologies and Innovation
2. Sequencing technologies
3. Health technologies
4. Digital Health
SECTION 2: Clinical care
5. Genetic counseling
6. Prenatal/Fetal Health
7. Precision Oncology
9. Orphan diseases
10. Cardiology
11. Pharmacogenomics
12. Clinical Care Coordination
13. Small molecule therapeutics
14. Gene and Cell based therapeutics
SECTION 3: Ethical, legal and social implications
15. Ethical/Legal/Social aspect
16. Patient Perspective
17. The Future
18. Take home message/Conclusion
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