非コードRNA生物学のための計算法 Computational Non-coding RNA Biology

Zheng, Yun

Academic Press Inc（2018/09発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 320 p.
• 言語 ENG
• 商品コード 9780128143650
• DDC分類 572.88

Full Description

Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different classes of non-coding RNAs and predicting the possible functions of these molecules.

Finding, quantifying, and visualizing non-coding RNAs from high throughput sequencing datasets at high volume is complex. Therefore, it is usually possible for biologists to complete all of the necessary steps for analysis.

Contents

PART 1 - BACKGROUND
1. Introductions

PART 2 - SMALL NCRNAS
2. Identification of microRNAs
3. Identification of TAS and PHAS
4. Identification of editing and mutation sites in miRNAs

PART 3 - MIRNA TARGETS
5. Identifying animal miRNA targets
6. Identifying plant miRNA targets

PART 4 - LONG NCRNAS 
7. Identification of long non-coding RNAs
8. Identification of lariat RNAs
9. Identification of circular RNAs

A. A usage guide of web-based ncRNA resources
B. Abbreviations and acronyms