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Full Description
Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development.
Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs' activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development.
Contents
1. Traditional systems of medicines and harmonization2. Ethnopharmacology and ethnomedicines-inspired drug development3. Quality evaluation of herbal medicines: Challenges and opportunities4. Qualitative analysis for evaluation of herbal drugs5. Morphological and microscopical evaluations6. Extraction and other downstream procedures for evaluation of herbal drugs7. Bioactive phyto-components and their analysis8. Thin layer chromatography for evaluation of herbal drugs9. High performance thin layer chromatography (HPTLC) for analysis of herbal drugs10. High performance liquid chromatography for analysis of herbal drugs11. LC-MS: A rapid technique for understanding the plant metabolomic analysis12. Chemo-profiling and marker analysis for quality evaluation of herbal drugs13. Bioassay guided isolation and evaluation of herbal drugs14. Enzyme inhibition studies for evaluation of herbal drugs15. Evaluation of herbal drugs for antimicrobial and parasiticidal effects16. Antiviral evaluation of herbal drugs17. Plant metabolomics and quality evaluation of herbal drugs18. Safety related quality issues for development of herbal drugs19. Quality assurance of herbal drugs and stability testing20. Phytopharmaceuitcals, nutraceuticals and their evaluation21. Regulatory harmonization and good quality practices for development of herbal medicine
