臓器とオルガノイド Organoids and Mini-Organs

Davies, Jamie A. (EDT)/ Lawrence, Melanie (EDT)

Academic Press Inc（2018/05発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 284 p.
• 言語 ENG
• 商品コード 9780128126363
• DDC分類 571.8

Full Description

Organs and Mini-Organs combines contributions from leading practitioners who work under the editorial control of an acclaimed researcher who also served for eight years as Editor-in-Chief of the journal Organogenesis, the first journal on this topic. The book begins with an introduction, but then delves into chapters that present advice on how to make organoids for many systems. In addition, case studies that illustrate the uses of organioids are presented, along with discussions on future directions and specific problems that need to be solved.

Contents

PART I INTRODUCTION
1. Organoids and mini-organs: Introduction, history, and potential

PART II CONSTRUCTING ORGANOIDS
2. Elements of organoid design
3. Intestinal organoids: Mini-guts grown in the laboratory
4. Three-dimensional breast culture models
5. Prostate organoids: Directed differentiation from embryonic stem cells
6. Kidney organoids
7. Spontaneous self-assembly of liver organoids from differentiated human cells
8. Cerebral organoids: Building brains from stem cells
9. From organoids to mini-organs: A case study in the kidney

PART III APPLICATIONS OF ORGANOIDS
10. Intestinal organoids: A model for biomedical and nutritional research
11. A three-dimensional neurosphere system using human stem cells for nanotoxicology studies
12. Organoids for modeling kidney disease
13. Intestinal organoids in studying host2bacterial interactions
14. Four challenges for organoid engineers