Full Description
Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation, Second Edition, provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of pharmacogenomics from academic, regulatory, pharmaceutical, socio-ethical and economic perspectives. While emphasis is on the limitations in moving the science into drug development and direct therapeutic applications, this book also focuses on clinical areas with successful applications and important initiatives that have the ability to further advance the discipline. New chapters cover important topics such as pharmacogenomic data technologies, clinical testing strategies, cost-effectiveness, and pharmacogenomic education and practice guidelines. The importance of ethnicity is also discussed, which highlights phar,acogenomic diversity across Latin American populations.With chapters written by interdisciplinary experts and insights into the future direction of the field, this book is an indispensable resource for academic and industry scientists, graduate students and clinicians engaged in pharmacogenomics research and therapeutic implementation.
Contents
1. Principles of Pharmacogenomics: Pharmacokinetic, Pharmacodynamic, and Clinical Implications
2. Governmental and Academic Efforts to Advance the Field of Pharmacogenomics
3. Incorporating Pharmacogenomics in Drug Development: Industry and Regulatory Perspectives
4. Translating Pharmacogenomic Research to Therapeutic Potentials
5. Pharmacogenomics in Cancer Therapeutics
6. Pharmacogenomics in Cardiovascular Diseases
7. Pharmacogenomics in Psychiatry Disorders
8. Role of Pharmacogenomics in HIV Infection
9. Role of Pharmacogenomics in Diabetes
10. A Look to the Future: Pharmacogenomics, Pharmacoepigenomics, and System Biology - Data Technologies of Today and Tomorrow
11. The Importance of Ethnicity Definitions and Pharmacogenomics in Ethnobridging and Pharmacovigilance
12. Pharmacogenomics in Latin American Population
13. Reactive, Point-of-Care, Pre-emptive and Direct-to-Consumer Pharmacogenomic Testing
14. Economic Evaluation of Pharmacogenomic Testing: Lessons from Psychiatric Pharmacogenomics
15. Pharmacogenomics Education and Clinical Practice Guidelines
