Full Description
Cardiovascular Thrombus: From Pathology and Clinical Presentations to Imaging, Pharmacotherapy and Interventions provides a comprehensive, up-to-date presentation of the research and clinical practices as related to the contemporary aspects of the diagnosis and management of cardiovascular thrombosis. The formation, identification and management of cardiovascular thrombus is of paramount importance for researchers and practicing physicians, yet it remains one of the most challenging diagnostic and clinical scenarios. This important reference connects between research, up-to-date clinical knowledge, and the technological tools available for diagnosis and management of thrombus in cardiovascular medicine. The book includes comprehensive descriptions and review of pathology, clinical presentations, diagnosis, pharmacotherapy, interventions and future trends.
It is the perfect reference for basic science students and researchers in general and interventional cardiology, general and interventional radiology, vascular medicine specialists, and vascular, general and cardiac surgeons.
Contents
Section 1. Pathology
1. Hemostasis and thrombosis
2. Vascular wall pathology- effect on thrombosis
3. Mechanisms of thrombosis and their relationship to atherosclerosis: Endothelial cell function and injury [trauma, infection]
4. Platelet aggregation in the pathogenesis of vascular ischemia conditions
5. Physical properties and morphologic features of thrombus
6. Pathology of arterial thrombosis
7. Thrombus types
8. The calcified thrombus: histopathology
9. Pathology of venous thrombosis
10. Hypercoagulopathy: acquired syndromes and thrombosis
11. Hypercoagulopathy: hereditary syndromes and thrombosis
12. Intra cardiac thrombosis: ventricles, atria, appendage and valves
13. Prosthetic surgical valves and TAVR thrombosis
14. Closure devices and thrombosis
Section 2. Clinical presentations
15. Thrombotic ischemic syndromes of the coronary circulation
16. Thrombotic ischemic syndromes of the brain
17. Thrombotic syndromes of the peripheral arterial circulation
18. Thrombosis of the splanchnic and mesenteric
19. Unique thrombus-containing lesions
20. Thrombosis of the venous system: DVT; portal vein; renal vein; Superior vena cava; Jugular; Budd-Chiari; cavernous sinus; cerebral
21. The angry thrombus phenomenon and the simultaneous thrombus in different vascular beds
22. Pulmonary embolism-acute
23. Pulmonary embolism: chronic
24. Platelets, thrombus and thrombosis in pregnancy
25. Atrial fibrillation and thromboembolism
Section 3. Diagnosis
26. Cardiovascular Thrombus classifications
27. Laboratory studies of thrombus and thrombosis
28. Imaging modalities
Section 4. Treatment Guidelines
29. The role of treatment guidelines-comparing the US and European approach to cardiovascular thrombus
Section 5. Pharmacotherapy
30. From Coumadin to the new anticoagulation agents
31. Antiplatelet agents: asa; heparins; LMH
32. Direct thrombin inhibitors
33. The 2b/3a receptor antagonists
34. Thienopyridines
35. Thrombolytic agents
Section 6. Interventions
36. Percutaneous approach:
37. Protection filters
38. Mechanical thrombectomy: Angiojet and X-Sizer
39. Stents: dedicated thrombus containing stent platforms
40. Extraction and vaporization devices: thrombocat and laser
41. LAA closure
42. Surgical approach
Section 6. Future trends
43. Pharmacotherapy and technology
