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Full Description
Gangliosides in Health and Disease, Volume 156, presents the latest information on Gangliosides, a class of glycolipids that are found on all vertebrate cell surfaces, and are particularly abundant in the brain. Individual chapters in this new volume cover Gangliosides as Toxin Receptors, Gangliosides in Cancer Cell Signaling, Gangliosides in inflammation and neurodegeneration, Gangliosides as functional galectin receptors, Gangliosides in signal transduction, Gangliosides in brain tumor immunology, and Gangliosides in axon regeneration and stability, amongst other related topics. This book brings together world experts in ganglioside structure and function who have been assembled to contribute to this thorough update of the field.
Contents
Preface and Ganglioside Nomenclature
Ronald L Schnaar, Pablo H. H. Lopez
1. Ganglioside Metabolism in Health and Disease
Roger Sandhoff, Heike Schulze, Konrad Sandhoff
2. Congenital Disorders of Ganglioside Biosynthesis
T. August Li, Ronald L. Schnaar
3. Gangliosides in Membrane Organization
Sandro Sonnino, Elena Chiricozzi, Sara Grassi, Laura Mauri, Simona Prioni, Alessandro Prinetti
4. Biological and Pathological Roles of Ganglioside Sialidases
Taeko Miyagi, Kohta Takahashi, Koji Yamamoto, Kazuhiro Shiozaki, Kazunori Yamaguchi
5. Biology of GM3 Ganglioside
Jin-ichi Inokuchi, Kei-ichiro Inamori, Kazuya Kabayama, Masakazu Nagafuku, Satoshi Uemura, Shinji Go, Akemi Suzuki, Isao Ohno, Hirotaka Kanoh, Fumi Shishido
6. Gangliosides in Cancer Cell Signaling
Sophie Groux-Degroote, Macarena Rodríguez-Walker, Justine H. Dewald, Jose L. Daniotti, Philippe Delannoy
7. Gangliosides in Diabetic Wound Healing
Duncan Hieu M. Dam, Amy S. Paller
8. Gangliosides in Nerve Cell Specification
Yutaka Itokazu, Jing Wang, Robert K. Yu
9. Gangliosides in Inflammation and Neurodegeneration
Koichi Furukawa, Yuhsuke Ohmi, Orie Tajima, Yuki Ohkawa, Yuji Kondo, Ji Shuting, Noboru Hashimoto, Keiko Furukawa
10. Glycan Chains of Gangliosides: Functional Ligands for Tissue Lectins (Siglecs/Galectins)
Robert W. Ledeen, Jürgen Kopitz, José Abad-Rodriguez, Hans-Joachim Gabius
11. Protein Toxins that Utilize Gangliosides as Host Receptors
Madison Zuverink, Joseph T. Barbieri
12. Gangliosides and Autoimmune Peripheral Nerve Diseases
John A. Goodfellow, Hugh J. Willison
13. Gangliosides in Axon Stability and Regeneration
Pablo H. H. Lopez, Bárbara B. Báez
14. Ganglioside-Mediated Assembly of Amyloid β-Protein: Roles in Alzheimer's Disease
Katsumi Matsuzaki, Koichi Kato, Katsuhiko Yanagisawa
15. Gangliosides, α-Synuclein and Parkinson's Disease
Robert W. Ledeen, Gusheng Wu
