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Full Description
Written by leading experts in the field, the fifth edition of the Cell Physiology Sourcebook, Fifth Edition offers a critical, comprehensive, and multidisciplinary overview of essential aspects of cell physiology and biophysics, spanning from bacterial and archaeal cells to mammalian cells and tissues. The present edition incorporates new molecular insights without losing the integrative perspective of cell physiology and biophysics, as well as its foundational concepts. Our target readers are advanced students and researchers interested in understanding how cells work.
The history of this book goes back to Hugh Davson's classic A Textbook of General Physiology, which reached its fourth and last edition in 1970. The successor of this influential work was Cell Physiology Sourcebook, first published in 1995 and edited by the late Professor Nicholas Sperelakis, with a foreword written by Davson. At that time, the knowledge of molecular and cell physiology became so vast that a single author's work, like its predecessor, was materially impossible. Professor Sperelakis, for whom we dedicate the present edition, put together an impressive volume with the contribution of various experts in fundamental areas of the field until the 4th edition, published in 2012, one year before his death. This book's success and the gap it fills motivated the present editors to continue this project, updating the entire book to reflect new developments.
Contents
SECTION I. BIOLOGICAL MEMBRANES AND CELL STRUCTURE
1. Biophysical Chemistry of Physiological Solutions
2. Physiological Structure and Function of Proteins
3. Carbohydrates - The Glycocalyx, and its Biological Roles
4. Cell Membranes
5. Bacterial and Archaeal Cells
6. Nucleic Acids and the Cell Nucleus
7. Structural and Biophysical Properties of Tight Junctions
8. Biology of Gap Junctions
9. Biophysics of Intracellular and Extracellular Diffusion
10. Membrane Diffusion and Permeability
11. Osmotic Pressure and Water Movement across Cell Membranes
12. Origin of Resting Membrane Potential
13. Energy Transduction in Biological Membranes
14. The F-ATP Synthase
15. Calcium Transport and Signaling
16. Intracellular Chloride Regulation
17. Intracellular pH Regulation
18. Trans-Epithelial Transport Mechanisms
19. Aquaporin Channels
20. Generation and Conduction of Electrical Signals
21. Structure and Mechanism of Voltage-Gated Channels
22. Mechanosensitive Channels: What Are They and Why Are They Important
23. Cell Volume Regulation
24. Ligand-Gated Channels
25. Signal Transduction
26. Synaptic Transmission
27. Pancreas and Insulin Secretion
28. Bioluminescence: Cell Physiology, Diversity and New Evolutionary Insights
29. Evolution and Physiology of Animal Visual Systems
30. Taste and Smell Chemoreceptors
31. Microtubules, Dynein and Eukaryotic Cilia
32. Motion by Rotary Flagella and Archaella, Twitching, Gliding Springs and Catapults
33. Cell Migration, Taxis, Kinesis, Quorum Sensing, and Tropism
34. Cell locomotion driven by actin gelation waves and actin-microtubule crosstalk
35. Chronobiology of Single-Cell Organisms
36. Smooth Muscle Excitability
37. Excitation-Contraction Coupling in Skeletal Muscle
