Full Description
The second edition of this classic reference deals exclusively with the biology and diseases of bone as they affect children. Rapid advances have been made in our understanding of the mechanisms and factors controlling the growth and development of bone, and these are discussed in detail in this book. Further, the various diseases of bone that are peculiar to children are highlighted and discussed in the light of our current knowledge with regard to causation, clinical signs and treatment. The book is aimed to provide those clinicians interested in children's diseases and basic scientists with a comprehensive resource covering the various aspects of bone health and disease in children.
Contents
1. Bone Cell Biology: Osteoblasts, Osteocytes, Osteoclasts
2. Bone Matrix and Mineralization
3. Prenatal Bone Development
4. Postnatal Bone Growth
5. Dental Development and Maturation
6. Parathyroid Hormone and Calcium Homeostasis
7. Phosphate Homeostasis Regulatory Mechanisms
8. Vitamin D Biology
9. Peak Bone Mass and Its Regulation
10. Pregnancy and Lactation
11. Fetal Mineral Homeostasis
12. Radiology
13. Noninvasisve Techniques for Bone Mass Measurement
14. Assessment of Skeletal Maturity
15. Biochemical Markers of Bone Metabolism
16. Pediatric Bone Histomorphometry
17. A Diagnostic Approach to Skeletal Dysplasias
18. The Spectrum of Pediatric Osteoporosis
19. Osteogenesis Imperfecta
20. Sclerosing Bone Dysplasias
21. Parathyroid Disorders
22. Fibrous Dysplasia
23. Nutritional Rickets
24. Metabolic Bone Disease in the Neonatal Period and its Later Sequelae
25. Hereditary Abnormalities of Vitamin D Synthesis or Action
26. Familial Hypophosphatemia and Related Disorders
27. Rickets Due to Tubular Abnormalities
28. Hypophosphatasia
29. Chronic Kidney Disease Mineral and Bone Disorder
30. Extraskeletal Bone Formation
