- ホーム
- > 洋書
- > 英文書
- > Science / Mathematics
Full Description
Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents.
Contents
1. Fundamentals of Viruses and Their Proteases
Anjana Sharma and Satya P. Gupta
2. Design and Development of Some Viral Protease Inhibitors by QSAR and Molecular Modeling Studies
Noha Saleh Hanan Elhaes and Medhat Ibrahim
3. Advances in Studies on Adenovirus Proteases and Their Inhibitors
Satya P. Gupta Basheerulla Shaik and Y. S. Prabhakar
4. Alpha-virus Nonstructural Proteases and Their Inhibitors
Akalabya Bissoyi, Subrat Kumar Pattanayak Arindam Bit Ashish Patel, Abhishek
5. Structure and Function of Alphavirus Protease
Shailly Tomar and Megha Aggarwal
6. Flavivirus Protease: An Antiviral Target
Shailly Tomar, Rajat Mudgal and Benazir Fatma
7. Flavivirus NSB/NS3 Protease: Structure, Function, and Inhibition
Zhong Li Jing Zhang Hongmin Li
8. Design and Development of HCV NS5B Polymerase Inhibitors
Debasis Das
9. Studies on HIV-1 Protease and its Inhibitors
Sonal Dubey
10. Studies on Picornaviral Proteases and Their Inhibitors
Vaishali M. Patil and Satya P. Gupta
11. Structural Insight into the Viral 3C-like Protease inhibitors: Comparative SAR/QSAR Approaches
Nilanjan Adhikari Sandip Kumar Baidya Achintya Saha, Tarun Jha
12. Herpesvirus Proteases: Structure, Function, and Inhibition
Kriti Kashyap and Rita Kakkar
13. Design and Development of Inhibitors of Herpes Viral Proteases and Their SAR and QSAR
Dimitra Hadjipavlou-Litina and Satya P Gupta
14. Delicate Dance in Treating Hepatitis C Infections and Overcoming Resistance
Dolly A. Parasrampuria
