Full Description
Advances in Pathobiology and Management of Paget's Disease of Bone presents an essential collection of up-to-date knowledge about the pathophysiology, genetics, and treatment of Paget's disease. It covers the comprehensive information related to clinical perspectives, epidemiology, genetics, environmental factors such as viral etiology, molecular abnormalities, complications such as osteosarcoma, and current and future treatment for Paget's disease. This book serves as a useful volume for basic scientists, graduate students, and practicing clinicians in understanding the pathobiology, etiology, and treatment of this disease.
Contents
1: Clinical Perspectives of Paget's disease of Bone
Tim Cundy, PhD
2: Virus etiology of Paget's disease
Sakamuri V. Reddy, PhD
3: Genetics of Paget's disease
Stuart H. Ralston,MD
4; Developmental aspects of pagetic osteoclasts
G. David Roodman, MD
5: Mutant SQSTM1/p62 signaling in Paget's disease of bone
Rob Layfield, PhD
6: Early-onset Paget's disease and related disorders: gene mutations and their functional consequences
Miep H Helfrich
7: Osteosarcoma in Paget's disease of bone
Marc F. Hansen, PhD
8: Paget's disease of bone; Prognosis and complications
Jacques P. Brown, MD
9: Treatment of Paget's disease
Ian R Reid, MD
