Full Description
Developing Costimulatory Molecules for Immunotherapy of Diseases highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy using either humanized antibodies against CD80, CD86, and other costimulatory molecules or CD28 fusinogenic proteins in the treatment of diseases, including allergies, asthma, rheumatoid arthritis, multiple sclerosis, lupus nephritis, severe psoriasis, vulgaris tuberculosis, thopoid, transplantation therapeutic, cancer, and inflammation.
The text aims to provide the latest information on the complex roles and interactions within the CD28 and B7 costimulatory families, with the hope that targeting these families will yield new therapies for the treatment of inflammation, autoimmunity, transplantation, cancer, and other infectious diseases.
Contents
Chapter 1: Introduction to costimulation and costimulatory molecules Chapter 2. Concept of reverse costimulation and its role in diseasesChapter 3. Costimulation immunotherapy in infectious diseasesChapter 4. Costimulation immunotherapy in allergies and asthmaChapter 5. Costimulation immunotherapy in lymphomas and cancerChapter 6. T cell costimulation and its applications in diseases
