Full Description
Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs.
The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer.
Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology.
Contents
Chapter 1. History and Early WorkChapter 2. Stellate Cell Culture ModelsChapter 3. Hepatic Fibrosis: A Global Clinical ProblemChapter 4. Stellate Cells and Hepatic FibrosisChapter 5. Cytokin Production and Signaling in Stellate CellsChapter 6. Stellate Cells, Portal Myofibroblasts and Epithelial-Mesenchymal TransitionChapter 7. Matrix Melalloproteinases and their InhibitorsChapter 8. Matrix Melalloproteinases and their InhibitorsChapter 9. Stellate Cells and Liver CancerChapter 10. Morphogens and hepatic stellate cell fate regulationChapter 11. Stellate Cells in alcoholic SteatohepatitisChapter 12. Stellate Cells as target for Reversal of Fibrosis/CirrhosisChapter 13. Interactions of Stellate Cells with other Nonparenchymal CellsChapter 14. Stellate Cells in Regulation of Hepatocyte Survival and FunctionsChapter 15. Stellate Cells in hepatic ImmunobiologyChapter 16. Stellate Cell Depletion ModelsChapter 17. Stellate Cells in Nonhepatic Organs
