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基本説明
Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, distinguishing this from other books that only focus on protocols for mouse developmental research.
Full Description
This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference.
Contents
Establishment of Body Pattern
Fertilization and Activation of the Embryonic Genome
Asymmetry and Pre-Pattern in Mammalian Development
Anterior Posterior Patterning of the Mouse Body Axis at Gastrulation
Left-Right Asymmetry
Patterning, Regionalization and Cell Differentiation in the Forebrain
Establishment of Anterior-Posterior and Dorsal-Ventral Pattern in the Early Central Nervous System
Somitogenesis: Segmentation of the Paraxial Mesoderm and the Delineation of Tissue Compartments
II. Lineage Specification and Differentiation
Extraembryonic tissues
Germ Cells
Development of the Vertebrate Hematopoetic System
Vasculogenesis and Angiogenesis
Stem Cells of the Nervous System
Cellular and Molecular Mechanisms Regulating Skeletal Muscle Development
Chondrogenesis and Skeletogenesis
III. Organogenesis
Development of the Endoderm and its Tissue Derivatives
Heart Development: Induction, Myogenesis and Patterning
Sex Determination and Differentiation
The Development of the Excretory System
Craniofacial Development
Pituitary Gland Development
Sensory Organs: Eye
Development of the Mouse Inner Ear
Integumentary Structures