Channels, Carriers, and Pumps : An Introduction to Membrane Transport （2ND）

Stein, Wilfred D./ Litman, Thomas

Academic Press Inc（2014/12発売）

• 製本 Hardcover:ハードカバー版／ページ数 422 p.
• 言語 ENG
• 商品コード 9780124165793
• DDC分類 574.875

Full Description

An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered.

Contents

ChaptersStructural Basis of Movement Across Cell MembranesSimple Diffusion of Nonelectrolytes and IonsIon Channels Across Cell MembranesCarrier-Mediated Transport: Facilitated DiffusionCoupling of Flows of Substrates: Antiporters and SymportersPrimary Active Transport SystemsThe Regulation and Integration of Transport SystemsAppendicesSingle and Triple-Letter Codes for the Amino AcidsFundamental Constants, Conversion Factors, and Some Useful ApproximationsThe Relation between the Permeability Coefficient Ps and the Half-Time t1/2 of Entry of a Permeant