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Full Description
This volume of The Enzymes features high-caliber thematic articles on the topic of glycosylphosphatidylinositol (GPI) anchoring of proteins.
Contents
CAAX Processing and yeast a-factor biogenesis
Jemima Barrowman and Susan Michaelis
Geranylgeranyltransferase-1 inhibitors
Norbert Berndt, Andrew D. Hamilton and Saïd M. Sebti
Small molecule inhibitors of GGTase-I from the heterocycle library derived from phosphine catalysis
Lai N. Chan, Masaru Watanabe, Ohyun Kwon and Fuyuhiko Tamanoi
Inhibition of Rab prenylation
E. Anouk Stigter, Gemma Triola, Roger S. Goody, Herbert Waldmann
The Ras Converting Enzyme (Rce1p): Orthologs, Enzymology and Inhibitors
Timothy M. Dore and Walter K. Schmidt
Cysmethynil, A Specific Small Molecule Inhibitor of Isoprenylcysteine Carboxylmethyl Transferase (Icmt)
Mei Wang
The Isoprenoid Biosynthetic Pathway and Statins
Sarah A. Holstein
Inhibition of Farnesyl and Geranylgeranyl Diphosphate Synthases
Sarah A. Holstein and Raymond J. Hohl