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Full Description
Streptococcus Pneumoniae: Molecular Mechanisms of Host-Pathogen Interactions provides a comprehensive overview of our existing knowledge on Streptococcus pneumoniae antibiotic resistance, dissemination, and pathogenesis, including immunology.
It presents a state-of-the-art overview of the implications of existing data, along with the areas of research that are important for future insights into the molecular mechanisms of pneumococcal infections and how to combat these infections.
Users will find a timely update on the topic, as the dramatic increase in antibiotic resistance pneumoniae cases and limitations of the currently available pneumoniae vaccines are creating new concerns on these gram-positive bacteria that are endowed with a high virulence potential, and are the most common etiologic agent of respiratory and life-threatening invasive diseases.
Contents
Section A: Streptococcus pneumoniae Epidemiology and Vaccines
1. Pneumococcal molecular epidemiology
2. Antibiotic resistance of pneuomocci
3. Pneumococcal vaccination and consequences
4. Protein based vaccines
Section B: Genetics and Functional Genomics of Streptococcus pneumoniae
5. Genomics, genetic variation and regions of differences
6. Functional Genomics of pneumococci (Transcriptional regulation)
7. Pneumococcal genetic recombination during colonization and biofilm formation
8. The pneumococcal cell wall
9. Capsule structure, synthesis and regulation
10. Pneumococcal ABC transporters and their role in physiology and multidrug resistance
Section C: Streptococcus pneumoniae Biology
11. Structure and functions of surface protein/choline binding proteins
12. Pneumococcal non-adhesive surface proteins
13. Biofilm formation under in vitro conditions
14. Pneumolysin
Section D: Pneumococcal Interactions with the Host
15. Nasopharyngeal colonization
16. Otitis media and biofilms
17. Pneumococcal pili and adhesins
18. Exploitation of host signal transduction pathways induced by S. pneuomoniae
19. Mechanisms of predisposition to pneumonia: infants, the elderly, and viral infections
20. Mechanisms causing the inflammatory response to Streptococcus pneumoniae
21. Immune evasion mechanisms of pneumococci
22. Cell mediated adaptive immunity to pneumococci
23. Pneumococcal invasion
