有機化学者のための創薬化学 Medicinal Chemistry for Organic Chemists

Aube, Jeffrey

Elsevier Science Ltd（2018/11発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 448 p.
• 言語 ENG
• 商品コード 9780123985330
• DDC分類 547

Full Description

Medicinal Chemistry for Organic Chemists provides an entry-level introduction to the field of medicinal chemistry for advanced chemistry undergraduate students and post-graduates. Written from the perspective of organic chemists, and in the language of chemists, this book provides the basic information required to understand the field of drug discovery. It presents and addresses common misconceptions and misunderstandings through the inclusion of key points, and supports the readers' further development through the inclusion of numerous references that point out key sources of in-depth information in the original literature.Underpinning the theoretical background, numerous development examples of real life pharmaceutical targets from key drug classes are shown, illustrating in a practical, memorable way how real world drug discovery takes place.

Contents

Part 11. Where do drugs come from and what are the roles of organic chemists in the drug discovery process?2. Fundamentals of human biology3. Pharmacology for chemists4. How do we begin? Where drug leads come from...5. Advancing leads to the clinic: Med chem tricks of the tradePart 2: Drug Classes: Examples and Lessons6. Orienteering through drug classes7. Neurology and Psychiatry8. Homeostasis, hormone control, and inflammation9. Infection10. Cancer