Full Description
This volume of Progress in Molecular Biology and Translational Science discusses cutting-edge research of proteasomes and proteasome-associated proteins and cellular systems. The volume is split into two sections. The first part discusses the current knowledge of the structure, function, and regulation of the proteasomal system. The second part describes the role of the proteasome in aging and disease.
Contents
Structure of the Proteasome
Tobias Jung and Tilman Grune
Structure and Function of the Ubiquitin-Proteasome System: Modulation of Components
Niki Chondrogianni and Efstathios S. Gonos
Immunoproteasomes: Structure, Function, and Antigen Presentation
Deborah A. Ferrington and Dale S. Gregerson
Interactions of the Proteasomal System with Chaperones - Protein Triage and Protein Quality Control
Marc Kästle and Tilman Grune
Proteasome Inhibitors
Boris Cvek
Degradation of Damaged Proteins - The Main Function of the 20S Proteasome
Andrew. M. Pickering and Kelvin. J. A. Davies
Changes of the Proteasomal System During the Aging Process
Martin A. Baraibar and Bertrand Friguet
Proteasome and Cancer
Betul Catalgol
The Ubiquitin Proteasome System and Cardiovascular Disease.
Saul R. Powell, Joerg Herrmann, Amir Lerman, Cam Patterson, Xuejun Wang
Role of the Ubiquitin-Proteasome in Protein Quality Control and Signaling: Implication in the Pathogenesis of Eye Diseases
Fu Shang and Allen Taylor
Proteasome and Neurodegeneratıve Dıseases
Betul Catalgol and Tilman Grune
