Full Description
This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as G protein-coupled receptor trafficking motifs, structure-based virtual screening, and automation-friendly high throughput assays for identification of pharmacoperone drugs.
Contents
GPCR Trafficking
Therapeutic Rescue of Misfolded/Mistrafficked Mutants: Automation-Friendly High Throughput Assays for Identification of Pharmacoperone Drugs of GPCRs
Trafficking of the Follitropin Receptor
Single Molecule Imaging Technique to Study the Dynamic Regulation of GPCR Function at the Plasma Membrane
GPCR Oligomerization and Receptor Trafficking
b-Arrestins and G Protein-Coupled Receptor Trafficking
Tracking Cell Surface Mobility of GPCRs Using α-Bungarotoxin Linked Fluorophores
Regulatory Mechanism of G Protein-Coupled Receptor Trafficking to the Plasma Membrane: A Role for mRNA Localization
Dissecting Trafficking and Signaling of Atypical Chemokine Receptors
Trafficking Motifs
Systematic and Quantitative Analysis of G Protein-Coupled Receptor Trafficking Motifs
Identification of Endoplasmic Reticulum Export Motifs for G Protein-Coupled Receptors
Amino Acid Residues of G-Protein Coupled Receptors Critical for Endoplasmic Reticulum Export and Trafficking
GPCR Oligomerization
G Protein-Coupled Heteromers Regulation in Disease
Hetero-Oligomerization and Specificity Changes of G Protein-Coupled Purinergic Receptors: Novel Insight into Diversification of Signal Transduction
Bimolecular Fluorescence Complementation Analysis of G Protein-Coupled Receptor Dimerization in Living Cells
G-Protein Coupled Receptor Heterodimerization in the Brain
Experimental Strategies for Studying G Protein-Coupled Receptor Homo- and Heteromerization with Radioligand Binding and Signal Transduction Methods
Analysis of GPCRs Dimerization Using Acceptor Photobleaching Resonance Energy Transfer Techniques
Techniques for the Discovery of GPCR-Associated Protein Complexes
Expression, Purification and Analysis of GProtein-Coupled Receptor Kinases
Modern Methods to Investigate the Oligomerization of Glycoprotein Hormone Receptors (TSHR,LHR, FSHR)
