基本説明
The most comprehensive up-to-date source covering basic principles, neural regulation, hormone/brain function and behavior, and neuroendocrine pathology. Heavily illustrated with over 350 figures, 4-color throughout.
Full Description
Neuroendocrinology, the discipline concerned with how the nervous system controls hormonal secretion and how hormones control the brain, is pivotal to physiology and medicine. Neuroendocrinology has disclosed and underpins fundamental physiological, molecular biological and genetic principles such as the regulation of gene transcription and translation, the mechanisms of chemical neurotransmission and intracellular and systemic feedback control systems. Reproduction, growth, stress, aggression, metabolism, birth, feeding and drinking and blood pressure are some of the bodily functions that are triggered and/or controlled by neuroendocrine systems. In turn, neuroendocrine dysfunction due to genetic or other deficits can lead, for example, to infertility, impotence, precocious or delayed puberty, defective or excessive growth, obesity and anorexia, Cushing's Syndrome, hypertension or thyroid disorders. These as well as neuroendocrine tumors are some of the themes covered in the 36 chapters of the Handbook. Drafted by internationally acknowledged experts in the field, the Handbook chapters feature detailed up-to-date bibliographies as well as "how do we know?" call out sections that highlight the experimental or technical foundations for major concepts, principles, or methodological advances in each area. Aimed at senior undergraduate and graduate students, post-doctoral fellows and faculty in neuroscience, medicine, endocrinology, psychiatry, psychology and cognate disciplines, the Handbook of Neuroendocrinology satisfies an unmet need that will prove useful at the laboratory bench as well as in the office.
Contents
Part I: Basic Principles of Neuroendocrinology
An introduction to neuroendocrine systems
Signaling in neuroendocrine systems
Neuroendocrine Control Systems
Part II: Neural Regulation of Endocrine Systems
Evolution of Neurohormones
Neural control of the anterior lobe of the pituitary gland (pars distalis)
Neural control of the posterior pituitary gland (neurohypophysis)
Neural Control of the Intermediate Lobe of the Pituitary Gland (Pars Intermedia) and Proopiomelanocortin
THE HYPOTHALAMIC PITUITARY ADRENAL AXIS AND NEUROENDOCRINE RESPONSES TO STRESS
Neuroendocrine Control of Reproduction
Lifetime Regulation of Growth-Hormone (GH) Secretion
NEUROENDOCRINE REGULATION OF DEVELOPMENT, GROWTH AND METABOLISM - THYROID
Circadian Rhythms in Neuroendocrine Systems
Cardiovascular control - renin angiotensin- AV3V - PVN
Part III: Hormones, Brain Function and Behavior
Neuroendocrine Regulation of Food Intake and Energy Homeostasis
Neuropeptide regulation of stress-induced behavior: insights from the CRF/Urocortin family
Neuroendocrine regulation of body water and electrolytes: Thirst and salt appetite
Sexual differentiation of brain and behavior
Corticosteroid actions on neurotransmission
Neuroendocrine Mechanism of Puberty
Sexual behaviors
Stress and brain function
Neuroendocrinology of Aggression
Chronic Social Stress: Effects on Neuroendocrine Function
Estrogen and Cognitive Aging in Women: The Critical Period Hypothesis
Hormones, mood and affect
Hormones and the aging brain
Part IV: Neuroendocrine Pathology
KALLMANN SYNDROME AND OTHER CAUSES OF HYPOTHALAMIC HYPOGONADISM AND RELATED DEVELOPMENT DISORDERS
Parental Behavior and the Perinatal Programming of Infant Development
Disorders of the hypothalamic-pituitary- adrenocortical system
Disorders of the Hypothalamic-Pituitary-Gonadal Axis
Disorders of the hypothalamic-pituitary- thyroid system
Neuroendocrine growth disorders - dwarfism - gigantism
Neuroendocrine inherited or induced aromatase enzyme deficits
Pituitary adenomas
Neuroendocrine carcinomas
Psychoneuroendocrinology
