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基本説明
40年以上に渡り、神経系の生化学の基礎から最新情報までを伝える決定番テキスト、6年ぶりの改訂。
The only complete advanced textbook that covers all major principles of neurochemistry and neurobiology. Over 400 fully revised figures in splended colour. 61 chapters covering the range of Cellular, Molecular and Medical neuroscience; Translational science boxes emphasizing the connections between basic and clinical neuroscience. 7th ed.: 2005.
Full Description
Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences.
The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology.
Contents
Part I: Cellular Neurochemistry and Neural Membranes Cell Biology of the Nervous SystemCell Membrane Structures and FunctionsMembrane TransportElectrical Excitability and Ion Channels Lipids The Cytoskeleton of Neurons and Glia Intracellular Trafficking Axonal Transport Cell Adhesion Molecules Myelin Structure and Biochemistry Energy Metabolism of the Brain
PART II: Intercellular Signaling Synaptic Transmission and Cellular Signaling: An Overview Acetylcholine Catecholamines Serotonin Histamine Glutamate and Glutamate ReceptorsGABA Purinergic Signaling Peptides
PART III: Intracellular SignalingG Proteins Cyclic Nucleotides in the Nervous System Phosphoinositides Calcium Serine and Threonine Phosphorylation Tyrosine Phosphorylation Transcription Factors in the Central Nervous System
PART IV: Growth, Development and Differentiation Development of the Nervous SystemGrowth Factors Stem Cells in the Nervous System Formation and Maintenance of MyelinAxonal Growth in the Adult Mammalian Nervous System
PART V: Cell Injury and Inflammation Molecular Mechanisms and Consequences of Immune and Nervous System ReactionsNeuroinflammationBrain Ischemia and Reperfusion: Cellular and Molecular Mechanisms in Stroke InjuryLipid Mediators: Eicosanoids, Docosanoids and Platelet-Activating Factor Apoptosis and Necrosis
PART VI: Inherited and Neurodegenerative Diseases Peripheral Neuropathy Diseases Involving Myelin The Epilepsies: Phenotypes and Mechanisms Genetics of Neurodegenerative Diseases Disorders of Amino Acid Metabolism Inborn Metabolic Defects of Lysosomes, Peroxisomes, Carbohydrates, and Fatty Acids and MitochondriaDisorders of Muscle Excitability Motor Neuron Diseases Neurobiology of Alzheimer's Disease Synucleinopathies and Tauopathies Cellular and Molecular Basis of Neurodegeneration in the CAG-Polyglutamine Repeat DiseasesNeurotransmitters and Disorders of the Basal Ganglia Molecular Basis of Prion Diseases
PART VII: Sensory Transduction Molecular Biology of Vision Molecular Biology of Olfaction and Taste Molecular Biology of Hearing and Balance Pain
PART VIII: Neural Processing and Behavior Endocrine Effects on the Brain and Their Relationship to Behavior Learning and Memory The Neurochemistry of Sleep and WakefulnessThe Neurochemistry of Schizophrenia The Neurochemistry of AutismNeurobiology of Severe Mood and Anxiety Disorders Addiction
