Full Description
This publication presents biokinetic models and best estimates of biokinetic data for some 120 individual radiopharmaceuticals, giving estimated absorbed doses, including the range of variation to be expected in pathological states, for adults, children and the fetus. Absorbed dose estimates are needed in clinical diagnostic work for judging the risk associated with the use of specific radiopharmaceuticals, both for comparison with the possible benefit of the investigation and to help in giving adequate information to the patient. These estimates provide guidance to ethics committees having to decide upon research projects involving the use of radioactive substances in volunteers who receive no individual benefit from the study. This report, while still an important source document, is supplemented and amended by ICRP Publication 80.
Contents
Preface. Quantities. General considerations of biokinetics and dosimetry. Introduction. Selection of radiopharmaceuticals. Selection of organs and tissues for dose calculations. Biokinetic models and data. Methods for calculating absorbed dose. Effective dose equivalent. Impurities in radiopharmaceutical preparations. References. Appendix A: Special biokinetic models. Appendix B: Calculation of absorbed dose to organs in cases where specific S-Values are not available. Biokinetic models, absorbed doses and effective dose equivalents for individual radiopharmaceuticals.
