Full Description
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Cutting-edge coverage of stem cell biology and applicationsFeaturing contributions from leading global experts, this authoritative volume addresses all major areas of stem cell biology and their potential therapeutic applications. The first part of the book covers embryonic stem cells and contains details on the emerging field of embryonic stem cell-based drug screening platforms. The second part deals with multipotent adult stem cells from different tissue types, and covers unique concepts such as cancer stem cells and tissue engineering-based approaches for designing microenvironments for tissue regeneration. Eighty pages of inserts with 113 color figures are included in this pioneering work.
Coverage includes:
Zebrafish, medaka, chicken embryonic, and mouse embryonic stem cells
Derivation of human embryonic stem cells (hESCs) from blastocysts
Treating diabetes with hESCs
hESCs as a model system to study human genetics
Application of hESCs in drug discovery
Adult stem cells for regenerative medicine and cancer therapies
Mesenchymal stem cells for neurodegenerative disease therapies
Dental pulp, hematopoietic, and spermatogonial stem cells
Epigenetic regulators of stem cell pluripotency
Cancer stem cells
Contents
List of Contributors; Foreword; Preface; Chapter 1. Stem Cells and Regenerative Medicine--The Evolving Story; Part 1: Embryonic Stem Cells; Chapter 2. Zebrafish Stem Cells; Chapter 3. Medaka Stem Cells; Chapter 4. Chicken Embryonic Stem Cells as Another Non-Mammalian Embryonic Stem Cell Type; Chapter 5. Derivation, Culture and Genetic Modification of Mouse Embryonic Stem Cells; Chapter 6. Derivation of Human Embryonic Stem Cells from Blastocysts; Chapter 7. Developing a Serum-free and a Novel Reporter System for hESCs; Chapter 8. Epigenetics and Embryonic Stem Cells; Chapter 9. Embryonic Stem Cells as Therapy for Diabetes; Chapter 10. Manipulation of Biomaterial Interface by Biomimetic Strategies: Possibilities of Exploring Stem Cells; Chapter 11. Immunomodulatory Aspects of Human Embryonic and Adult Stem Cells; Chapter 12. Human Embryonic Stem Cells as a Model System to Study Human Genetics; Chapter 13. Germ Cells and Artificial Gametes Production from Embryonic Stem Cells; Chapter 14. Using Embryonic Stem Cells to Introduce Mutations into the Mouse Germ Line: Animal Models and Future Applications; Chapter 15. Application of Human Embryonic Stem Cells in Drug Discovery; Part 2: Adult Stem Cells; Chapter 16. Recent Advancements on Tissue-Resident Adult Stem/Progenitor Cell Biology and Their Therapeutic Applications in Regenerative Medicine and Cancer Therapies;Chapter 17. Mesenchymal Stem Cells and their Therapeutic Potential in the Nervous System; Chapter 18. Mesenchymal Stem Cells: Culture Optimization and Potential Clinical Use; Chapter 19. Mesenchymal Stem Cells: Culture, Characterization and Therapeutic Applications in Neurodegenerative Diseases; Chapter 20. Dental Pulp Stem Cells and Perspectives of Future Application in Cell Therapy; Chapter 21. Hematopoletic Stem Cells and Their Dynamics; Chapter 22. Spermatogonial Stem Cells; Chapter 23. Epigenetics as a Cause for the Eloquent Silence of Stem Cells; Chapter 24. Cancer Stem Cells: The Enemy within Cancers; Chapter 25. Exploring the Potential of Adult Stem Cells: Why Umbilical Cord Blood?; Chapter 26. Cell Therapy and Tissue Engineering in Regenerative Medicine; Chapter 27. Biomaterials for Enhancing Corneas and Spinal Cord Regeneration; Index
