Description
Advances in CRISPR/Cas and related technologies, Volume 179, the latest release in this ongoing series, deals with a wide variety of research topics related to recent advancement in the genome editing techniques. Associated chapters in this new release include Challenges for Therapeutic application of CRISPR Cas techniques, Mitochondrial DNA modification by CRISPR Cas System: Challenges and future direction, Trends in CRISPR Cas technology application in cancer, Modified CRISPR-Cas for next generation application, Application of CRISPR Cas in Synthetic Biology: Challenges and Scopes, History of CRISPR Cas system from bacterial Adaptive Immune System to research application, and more.
- Covers the Cas9 protein modification for reduced off-target effect
- Includes discussions on Cas9 utilization for Metabolic Engineering
- Provides information on the use of Cas9 for targeted delivery in therapeutic application
Table of Contents
1. The evolution and history of gene editing technologies
Shubhchintan Randhawa and Shatakshi Sengar
2. CRISPR-Cas9: A fascinating journey from bacterial immune system to human gene editing
Munshi Azad Hossain
3. Modification of Cas9, gRNA and PAM: Key to further regulate genome editing and its applications
Rahul Gupta, Darshana Gupta, Kazi Tawsif Ahmed, Dhritiman Dey, Rajveer Singh, Snehasikta Swarnakar, V. Ravichandiran, Syamal Roy and Dipanjan Ghosh
4. CRISPR/dCas system as the modulator of gene expression
Tawsif Ahmed Kazi and Swadesh Ranjan Biswas
5. CRISPR-Cas system, antibiotic resistance and virulence in bacteria: Through a common lens
Subhasree Roy, Sharmi Naha, Ankur Rao and Sulagna Basu
6. Trends in CRISPR-Cas9 technology application in cancer
Subhadip Mukhopadhyay and Sujit Kumar Bhutia
7. Mitochondrial DNA modification by CRISPR/Cas system: Challenges and future direction
Rajalakshmi Prakash and Anbarasu Kannan
8. Immune responses to CRISPR-Cas protein
Sobhan Roy
9. CRISPR’s got some nerves: Application of CRISPR-Cas systems in neuroscience
Deepro Bonnerjee and Sangram Bagh
