Description
Dopamine is a small molecule traditionally regarded as a brain-derived neuronal modulator implicated in many neurological and psychiatric disorders. Outside the brain, dopamine fulfills all the criteria of a circulating hormone which affects normal and abnormal functions of multiple organs and regulatory systems and is also involved in many aspects of cancer formation and progression. This book provides a much needed systematic account of dopamine as an endocrine and autocrine/paracrine hormone and fills a major gap in the overall understanding of the production, distribution and actions of this very important molecule.
Key Features:
- Explores the many different faces of dopamine as autocrine, paracrine and endocrine molecule
- Documents the adverse effects of antipsychotics on dopamine functions
- Reviews the many ways dopamine affects the cardiovascular, renal and reproductive systems
- Provides updates on receptor oligomerization and signaling
- Examines the role of dopamine in tumorigenesis
Related Titles
Jones, S. ed. Dopamine - Glutamate Interactions in the Basal Ganglia (ISBN 978-0-3673-8197-4)
Luo, L. Principles of Neurobiology (ISBN 978-0-8153-4494-0)
Sidhu, A. et al., eds. Dopamine Receptors and Transporters (ISBN 978-0-8247-0854-2)
Table of Contents
Chapter 1: Homeostasis of dopamine.
Chapter 2: Dopamine receptors and their signaling.
Chapter 3: Anatomical and endocrine aspects of brain dopamine.
Chapter 4: Attributes of peripheral dopamine.
Chapter 5: Renal and cardiovascular functions of dopamine.
Chapter 6: Digestive and metabolic actions of dopamine.
Chapter 7: Dopamine and hematopoiesis.
Chapter 8: Regulation of reproduction by dopamine.
Chapter 9: Cutaneous actions of dopamine.
Chapter 10: Dopamine and tumorigenesis in reproductive tissues.
Chapter 11: Dopamine, hematologic and GI-related cancers.
Chapter 12: Actions of dopamine on other cancers. Summary and Perspectives
